Equity in genomic medicine

CH Halbert - Annual Review of Genomics and Human Genetics, 2022 - annualreviews.org
Since the completion of the Human Genome Project, considerable progress has been made
in translating knowledge about the genetic basis of disease risk and treatment response into …

Challenges and potential solutions to health disparities in genomic medicine

SSJ Lee, PS Appelbaum, WK Chung - Cell, 2022 - cell.com
Significant disparities in the clinical usefulness of genomic information across diverse
groups are due to underrepresentation in genetic databases and inequitable access to …

[HTML][HTML] Defining and achieving health equity in genomic medicine

S Jooma, MJ Hahn, LA Hindorff, VL Bonham - Ethnicity & disease, 2019 - ncbi.nlm.nih.gov
The potential of genomics to improve health comes with the peril that the benefits will not be
equitably available to all populations. Existing health disparities can be exacerbated if the …

[HTML][HTML] Health equity in the implementation of genomics and precision medicine: A public health imperative

MJ Khoury, S Bowen, WD Dotson, E Drzymalla… - Genetics in …, 2022 - Elsevier
Recent reviews have emphasized the need for a health equity agenda in genomics
research. To ensure that genomic discoveries can lead to improved health outcomes for all …

Equity in health: consideration of race and ethnicity in precision medicine

TL Edwards, J Breeyear, JA Piekos, DRV Edwards - Trends in Genetics, 2020 - cell.com
The causes for disparities in implementation of precision medicine are complex, due in part
to differences in clinical care and a lack of engagement and recruitment of under …

Enhancing diversity to reduce health information disparities and build an evidence base for genomic medicine

LA Hindorff, VL Bonham… - Personalized Medicine, 2018 - Taylor & Francis
Advances in genomic medicine are arising from efforts to build a national learning
healthcare system (LHS) and large-scale precision medicine studies. However, the …

Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health

GQ Shaibi, IJ Kullo, DP Singh, V Hernandez… - Genetics in …, 2020 - nature.com
Purpose This report describes the return of sequencing results to low-income Latino
participants recruited through a Federally Qualified Health Center (FQHC). We describe …

Advancing genomics to improve health equity

EB Madden, LA Hindorff, VL Bonham, TH Akintobi… - Nature …, 2024 - nature.com
Health equity is the state in which everyone has fair and just opportunities to attain their
highest level of health. The field of human genomics has fallen short in increasing health …

[HTML][HTML] How can law support development of genomics and precision medicine to advance health equity and reduce disparities?

SM Wolf, VL Bonham, MA Bruce - Ethnicity & Disease, 2019 - ncbi.nlm.nih.gov
There is growing recognition that the genomic and precision medicine revolution in health
care can deepen health disparities. This has produced urgent calls to prioritize inclusion of …

[HTML][HTML] Leveraging implementation science to address health disparities in genomic medicine: examples from the field

MC Roberts, GA Mensah, MJ Khoury - Ethnicity & disease, 2019 - ncbi.nlm.nih.gov
The integration of genomic data into screening, prevention, diagnosis, and treatment for
clinical and public health practices has been slow and challenging. Implementation science …