Electronegative low-density lipoprotein (LDL (−)) is a minor modified LDL subfraction that is
present in blood. LDL (−) promotes inflammation and is associated with the development of …

Firm epidemiological and clinical evidence shows that an increased LDL-cholesterol level is
proatherogenic and an increased HDL-cholesterol level is antiatherogenic. This is fully …

Aim: Modified low-density lipoprotein (mLDL), mainly upon oxidative and enzymatic
modification, is the major atherogenic lipoprotein. Conversely, high-density lipoprotein …

Recent findings suggest that low-density lipoprotein (LDL), a normal constituent of blood
plasma, may exert a 'hormone-like'action Lutz Block and AlfrA Pletscher show that LDL, at …

Introduction 3. Current Knowledge 3.1. LDLR family members cooperate with other cell
surface proteins to mediate ligand endocytosis 3.2. Roles of LDLR family members in …

Operationally, low density lipoprotein (LPL) is defined as the lipoprotein class that is isolated
in the density range 1.019-1.063. It possesses beta motility on electrophoresis. It is the most …

Since the discovery of LDLR, knowledge about its function has greatly expanded. As a result
of its importance in maintaining homeostatic LDL levels, the LDLR pathway has emerged as …

Although the epidemiology of high-density lipoprotein (HDL) cholesterol and cardiovascular
risk has been consistent, pharmacologic interventions to increase HDL-cholesterol by …

Cardiovascular disease is the number one killer in the US, and atherosclerosis is the major
cause of heart disease and stroke (1). It is widely appreciated that cholesterol plays an …

Low‐density lipoprotein (LDL) plays a key role in the development and progression of
atherosclerosis and cardiovascular disease. LDL consists of several subclasses of particles …