Recent advances in physiological lipoprotein metabolism

I Ramasamy - Clinical Chemistry and Laboratory Medicine (CCLM), 2014 - degruyter.com
Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

Spotlight on HDL biology: new insights in metabolism, function, and translation

DJ Rader - Cardiovascular Research, 2014 - academic.oup.com
High-density lipoproteins (HDLs) have captured the imagination of scientists and physicians
from virtually the time they were originally described, but especially after the cholesterol …

2 Lipoproteins and atherosclerosis

J Babiak, LL Rudel - Bailliere's clinical endocrinology and metabolism, 1987 - Elsevier
The plasma lipoproteins are the primary means of transport of cholesterol among tissues. In
particular, the apo B-containing lipoproteins (VLDL, IDL and LDL) are important for the …

Dysfunctional high-density lipoproteins in coronary heart disease: implications for diagnostics and therapy

W Annema, A von Eckardstein - Translational Research, 2016 - Elsevier
Low plasma levels of high-density lipoprotein (HDL) cholesterol are associated with
increased risks of coronary heart disease. HDL mediates cholesterol efflux from …

Lipoprotein receptor signalling in atherosclerosis

C Mineo - Cardiovascular research, 2020 - academic.oup.com
The founding member of the lipoprotein receptor family, low-density lipoprotein receptor
(LDLR) plays a major role in the atherogenesis through the receptor-mediated endocytosis …

Lipids and Lipoproteins in Atherosclerosis

E Bezsonov, V Khotina, V Glanz, I Sobenin, A Orekhov - Biomedicines, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory disease [1, 2] which manifests in the pathological
thickening of the walls of large arteries, and is related to lipid depositions. Lipids, including …

The role of small, dense low density lipoprotein (LDL): a new look

C Packard, M Caslake, J Shepherd - International journal of cardiology, 2000 - Elsevier
Plasma low density lipoprotein (LDL) plays a central role in atherogenesis, and elevated
levels of LDL are associated with an increased risk of coronary heart disease (CHD) …

Possible non-classic intracellular and molecular mechanisms of LDL cholesterol action contributing to the development and progression of atherosclerosis

I Gouni-Berthold, A Sachinidis - Current Vascular …, 2004 - ingentaconnect.com
Elevated low density lipoprotein (LDL) cholesterol (LDL-C) levels represent one of the most
important risk factors for atherosclerosis and therefore cardiovascular morbidity and …

Low density lipoprotein receptor regulation and the cellular basis of atherosclerosis: implications for nutritional and pharmacologic treatment of hypercholesterolemia

D Heber, BJ Koziol, LC Henson - The American Journal of Cardiology, 1987 - Elsevier
Blood levels of lipids and lipoproteins are prominent among the factors identified as
contributing to the development of coronary artery disease. Studies have demonstrated that …

Some questions concerning a small, more electronegative LDL circulating in human plasma

P Avogaro, G Cazzolato, G Bittolo-Bon - Atherosclerosis, 1991 - Elsevier
Atherosclerosis and its complications are prevalent worldwide with a high prevalence in
western societies. The disease may sometimes be explained by a defect of low density …