Background: Glioblastoma multiforme (GBM) is the most aggressive and malignant primary
brain tumor characterized by rapid growth and extensive infiltration to neighboring normal …

Purpose: To study the antiproliferative effects of myricetin in human glioma U251 cells
together with assessing its effects on cell cycle, apoptosis, apoptosis-related proteins …

Eriodictyol (ERD) is a natural flavonoid that exists in many vegetables and fruits, especially
citrus fruits. It has been proven to have many pharmacological effects, such as antioxidative …

Pelargonidin has attracted much attention in many cancers. Whether the growth of glioma
inhibited by pelargonidin is related to the PI3K/AKT/mTOR pathway is unknown. To examine …

Shikonin is an anthraquinone derivative extracted from the root of lithospermum. Shikonin is
traditionally used in the treatment of inflammatory and infectious diseases such as hepatitis …

The recurrence and metastasis of hepatocellular carcinoma (HCC) are a major concern in
current research. Epithelial‑mesenchymal transition (EMT) is the leading cause underlying …

Myricetin is a typical flavonol with various pharmacological effects which shows favorable
biological activities in cancer. However, the underlying mechanisms and potential targets of …

Cancer is a major public health concern worldwide and main burden of the healthcare
system. Regrettably, most of the currently used cancer treatment approaches such as …

High invasiveness is a biological and clinical characteristic of glioblastoma and predicts
poor prognosis of patients. Quercetin, a natural flavonoid compound, exhibits anticancer …

The gaps between the complex nature of cancer and therapeutics have been narrowed
down due to extensive research in molecular oncology. Despite gathering massive insight …