Colchicine as an anti-inflammatory and cardioprotective agent

AY Gasparyan, L Ayvazyan… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Colchicine has been successfully used for the treatment of neutrophilic
disorders such as familial Mediterranean fever (FMF), Behçet disease (BD) and gout. There …

Colchicine for the treatment of cardiovascular diseases: old drug, new targets

A Andreis, M Imazio, GM De Ferrari - Journal of Cardiovascular …, 2021 - journals.lww.com
Well known in past centuries as a herbal remedy for osteoarticular pain and commonly used
in the treatment of gout and familial Mediterranean fever, colchicine has an emerging role in …

Colchicine for cardiovascular medicine

M Imazio, F Gaita - Future Cardiology, 2016 - Future Medicine
Colchicine is an ancient drug with anti-inflammatory effects especially on neutrophils. These
cells are critically involved in pericardial and atherosclerotic plaques inflammation, thus …

The use of colchicine in cardiovascular diseases: a systematic review

J Siak, N Flint, HG Shmueli, RJ Siegel… - The American Journal of …, 2021 - Elsevier
The medicinal properties of colchicine have been recognized for centuries. Although
previously used for gout and familial Mediterranean fever, its immune-modulating, anti …

Colchicine in cardiovascular disease: in-depth review

SG Deftereos, FJ Beerkens, B Shah, G Giannopoulos… - Circulation, 2022 - Am Heart Assoc
Inflammation plays a prominent role in the development of atherosclerosis and other
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular …

Colchicine: an old wine in a new bottle?

F Roubille, E Kritikou, D Busseuil… - Anti-Inflammatory & …, 2013 - ingentaconnect.com
Although colchicine, a natural product, is one of the oldest drugs still currently available, its
possible functions seem to be surprisingly not well-known. Beyond its present medicinal use …

Colchicine and the heart

M Imazio, M Nidorf - European Heart Journal, 2021 - academic.oup.com
Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for
decades for the prevention of acute inflammatory flares in gout and familial Mediterranean …

Colchicine and the heart: pushing the envelope

S Deftereos, G Giannopoulos, N Papoutsidakis… - Journal of the American …, 2013 - jacc.org
Colchicine, a natural and ancient drug still used today, is traditionally considered the staple
therapy for gout and a second-line treatment for pericarditis, as well as a basic part of …

Repurposing colchicine for heart disease

N Bouabdallaoui, JC Tardif - Annual Review of Pharmacology …, 2022 - annualreviews.org
Colchicine is one of the most ancient medications still prescribed. It is extracted from the
Colchicum autumnale plant and is routinely used because of its broad anti-inflammatory …

Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials

S Verma, JW Eikelboom, SM Nidorf… - BMC Cardiovascular …, 2015 - Springer
Background Colchicine has unique anti-inflammatory properties that may be beneficial in
various cardiovascular conditions. This systematic review and meta-analysis of randomized …