Background The prognostic value of tumor‐associated dendritic cells (DC) in colon cancer
remains poorly understood. This may be in part due to the interchangeable expression of …

The question as to whether the tumor grows because of or despite the host immune system
is being progressively addressed with refined technology, gene targeting in mice and …

Dendritic cells (DCs) orchestrate a repertoire of immune responses that bring about
resistance to infection and tolerance to self. Cancers can exploit DCs to evade immunity, but …

Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular
development and enable evasion of anti-tumour immune responses, by disabling infiltrating …

Dendritic cells (DCs) play a crucial role in linking innate and adaptive immunity and, thus, in
the generation of a protective immune response against both infectious diseases and …

Dendritic cells (DCs) constitute a complex network of cell subsets with common functions but
also with many divergent aspects. All dendritic cell subsets share the ability to prime T cell …

The role of dendritic cells in the immune system has been the subject of intense study for the
past two decades, and it is now beyond question that these cells play a critical role in …

Protumorigenic activity of immune regulatory cells has been proven to play a major role in
precluding immunosurveillance and limiting the efficacy of anticancer therapies. Although …

Dendritic cells are the most potent 'professional'antigen-presenting cells, with high ability of
primary immune response initiation. Dendritic cells originate from bone marrow progenitors …

Simple Summary Although immune check point inhibitors have been established as a new
paradigm in cancer treatment, they have shown no clinical benefit in immune excluded or …