Dendritic cells (DC) play unique and diverse roles in the tumor occurrence, development,
progression and response to therapy. First of all, DC can actively uptake tumor-associated …

Cytotoxic CD8+ T cells are potent killers of diseased cells, but their functional capacity is
often compromised in cancer. The quality of antitumor T cell immunity is determined during T …

Dendritic cells (DCs), including conventional DCs (cDCs) and plasmacytoid DCs (pDCs),
serve as the sentinel cells of the immune system and are responsible for presenting antigen …

Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and maintain
immunity and tolerance. DCs initiate immune responses in a manner that depends on …

The failure of the immune system to provide protection against tumour cells is an important
immunological problem. It is now evident that inadequate function of the host immune …

The tumour microenvironment (TME) presents a major block to anti-tumour immune
responses and to effective cancer immunotherapy. The inflammatory mediators such as …

Abstract Development and progression of malignancies are accompanied and influenced by
alterations in the surrounding immune microenvironment. Understanding the cellular and …

Full article: Tumor conditioned media from colorectal cancer patients inhibits dendritic cell
maturation Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …

Several lines of evidence from recent years support the existence of cancer
immunosurveillance, especially studies of natural killer (NK) cells and the IFN-pathway …

Simple Summary Dendritic cells (DCs) are an important type of immune cell present in the
blood and tissues, capable of detecting potential threats and displaying them to lymphocytes …