Dendritic cells (DCs) are the principal antigen-presenting cells of the immune system and
play key roles in controlling immune tolerance and activation. As such, DCs are chief …

Though present in low numbers, dendritic cells (DCs) are recognized as major players in the
control of cancer by adaptive immunity. The roles of cytotoxic CD8+ T-cells and Th1 helper …

Dendritic cells (DCs) are essential for the maintenance of homeostasis in the organism, and
they do that by modulating lymphocyte priming, expansion, and response patterns according …

Dendritic cells (DCs) contribute a small fraction of the tumor microenvironment but are
emerging as an essential antitumor component based on their ability to foster T cell …

Background Plasmacytoid dendritic cells (pDCs) play a key role in the induction and
maintenance of antitumor immunity. Conversely, they can act as tolerogenic DCs by …

Dendritic cells (DCs) are central to the initiation of tumor-specific immune responses.
However, the tumor microenvironment generates immunosuppressive cells and soluble …

Objective: Dendritic cells (DC) are central to the development of immune system responses.
In a cohort of 54 patients affected by colorectal cancer, we prospectively investigated the …

The tumor microenvironment is a pivotal factor in tumorigenesis, and especially in
progression, as the pathogenesis of cancer critically depends on the complex interactions …

Researchers and clinicians have tried for decades to use the mechanisms of immunity for
the fight against cancer. Early attempts aimed at the instrumentation of soluble immune …

Dendritic cells (DCs), as specialized antigen-presenting cells, are essential for the initiation
of specific T cell responses in innate antitumor immunity and, in certain cases, support …