Neuropsychiatric disorders are often associated with motor and coordination abnormalities
that have important implications on the etiology, pathophysiology, and management of these …

In humans, infancy and adolescence are associated with major changes in synaptic
functions and ongoing maturation of neural networks, which underlie the major behavioral …

Pharmacological and toxicological studies in neurodegeneration require comprehensive
behavioral analysis in mice because motor dysfunctions and dysfunctions in mood and …

The behavioral characterization of animal models of psychiatric disorders is often based
upon independent traits measured at adult age. To model the neurodevelopmental aspects …

Between adolescence and adulthood, the brain critically undergoes maturation and
refinement of synaptic and neural circuits that shape cognitive processing. Adolescence also …

Background Motor impairments are amongst the earliest and most consistent signs of autism
spectrum disorders but are not used as diagnostic criteria. In addition, the relationship …

Abstract Mouse models of Autism Spectrum Disorder (ASD) have been interrogated using a
variety of behavioral tests in order to understand the symptoms of ASD. However, the …

Behavior provides important insights into neuronal processes. For example, analysis of
reaching movements can give a reliable indication of the degree of impairment in …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …

Neurodevelopmental disorders (NDDs) are highly prevalent and severely debilitating brain
illnesses caused by aberrant brain growth and development. Resulting in cognitive, social …