Obstructive sleep apnea (OSA) has become major public concern and is continuously
investigated in new aspects of pathophysiology and management. Urotensin II (UII) is a …

Up to date, human urotensin II (UII) is the most potent vasoconstrictor in mammalian
animals. To explore whether UII played an important role in the development of …

Objective We aimed to evaluate the controversial association between human urotensin II
and essential hypertension in untreated hypertensive cases and normotensive controls …

Abstract Objective Human urotensin II (UII) acts on the urotensin (UT) receptor and is the
most potent mammalian vasoconstrictor identified to date. The role of UII in human …

Urotensin II (UII) is an 11 amino acid cyclic peptide originally isolated from the goby fish. The
amino acid sequence of UII is exceptionally conserved across most vertebrate taxa, sharing …

J Clin Hypertens (Greenwich). 2010; 12: 653–660.© 2010 Wiley Periodicals, Inc. Urotensin II
(UII) exerts multiple effects on the cardiovascular system, acts as a diabetogenic agent, and …

The peptide urotensin-II (U-II) has been described as most potent vasoconstrictor identified
so far, but plasma values in humans and its role in cardiovascular pathophysiology are …

Background: Circulating blood levels of human urotensin II (U-II), the most potent
vasoconstrictor peptide identified to date, are increased in patients with essential …

Highlights•Urotensin II is a cyclic undecapeptide involved in cardiovascular
regulation.•Pseudo-irreversible binding to UT receptor could explain urotensin II low …

Human urotensin II (U-II), the most potent vasoconstrictor undecapeptide identified to date,
and its receptor (UT) are involved in the pathogenesis of systemic and pulmonary …