Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data
Tumor formation is in part driven by DNA copy number alterations (CNAs), which can be
measured using microarray-based Comparative Genomic Hybridization (aCGH) …
measured using microarray-based Comparative Genomic Hybridization (aCGH) …
CGH microarrays and cancer
A Kallioniemi - Current opinion in biotechnology, 2008 - Elsevier
Genetic alterations are a key feature of cancer cells and typically target biological processes
and pathways that contribute to cancer pathogenesis. Array-based comparative genomic …
and pathways that contribute to cancer pathogenesis. Array-based comparative genomic …
Hidden Markov models approach to the analysis of array CGH data
J Fridlyand, AM Snijders, D Pinkel, DG Albertson… - Journal of multivariate …, 2004 - Elsevier
The development of solid tumors is associated with acquisition of complex genetic
alterations, indicating that failures in the mechanisms that maintain the integrity of the …
alterations, indicating that failures in the mechanisms that maintain the integrity of the …
KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data
JJ de Ronde, C Klijn, A Velds, H Holstege… - BMC research …, 2010 - Springer
Background Most approaches used to find recurrent or differential DNA Copy Number
Alterations (CNA) in array Comparative Genomic Hybridization (aCGH) data from groups of …
Alterations (CNA) in array Comparative Genomic Hybridization (aCGH) data from groups of …
Estimation of tumor heterogeneity using CGH array data
K Wang, J Li, S Li, L Bolund, C Wiuf - BMC bioinformatics, 2009 - Springer
Background Array-based comparative genomic hybridization (CGH) is a commonly-used
approach to detect DNA copy number variation in whole genome-wide screens. Several …
approach to detect DNA copy number variation in whole genome-wide screens. Several …
Experimental design and data analysis for array comparative genomic hybridization
PJ Park - Cancer investigation, 2008 - Taylor & Francis
Array comparative genomic hybridization (aCGH) is a technique for measuring
chromosomal aberrations in genomic DNA. With the availability of high-resolution …
chromosomal aberrations in genomic DNA. With the availability of high-resolution …
Genomic microarrays in human genetic disease and cancer
DG Albertson, D Pinkel - Human molecular genetics, 2003 - academic.oup.com
Alterations in the genome that lead to changes in DNA sequence copy number are a
characteristic of solid tumors and are found in association with developmental abnormalities …
characteristic of solid tumors and are found in association with developmental abnormalities …
Bayesian random segmentation models to identify shared copy number aberrations for array CGH data
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
Analysis of array CGH data: from signal ratio to gain and loss of DNA regions
Motivation: Genomic DNA regions are frequently lost or gained during tumor progression.
Array Comparative Genomic Hybridization (array CGH) technology makes it possible to …
Array Comparative Genomic Hybridization (array CGH) technology makes it possible to …
Analysis of array CGH data for cancer studies using fused quantile regression
Y Li, J Zhu - Bioinformatics, 2007 - academic.oup.com
Motivation: The identification of DNA copy number changes provides insights that may
advance our understanding of initiation and progression of cancer. Array-based comparative …
advance our understanding of initiation and progression of cancer. Array-based comparative …