Estimating the risks of prehospital transfusion of D‐positive whole blood to trauma patients who are bleeding in England

R Cardigan, T Latham, A Weaver, M Yazer… - Vox …, 2022 - Wiley Online Library
Background and Objectives D‐negative red cells are transfused to D‐negative females of
childbearing potential (CBP) to prevent haemolytic disease of the foetus and newborn …

Not as “D” eadly as once thought–the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma

MH Yazer, G Panko, JB Holcomb, A Kaplan… - …, 2023 - Taylor & Francis
The use of blood products to resuscitate injured and massively bleeding patients in the
prehospital and early in-hospital phase of the resuscitation is increasing. Using group O red …

Modelling the outcomes of different red blood cell transfusion strategies for the treatment of traumatic haemorrhage in the prehospital setting in the United Kingdom

B Roberts, L Green, V Ahmed, T Latham… - Vox …, 2022 - Wiley Online Library
Abstract Background and Objectives The limited supply and increasing demand of group O
RhD‐negative red blood cells (RBCs) have resulted in other transfusion strategies being …

The risk to future pregnancies of transfusing Rh (D)‐negative females of childbearing potential with Rh (D)‐positive red blood cells during trauma resuscitation is …

JN Seheult, MN Stram, T Pearce, CB Bub… - Vox …, 2021 - Wiley Online Library
Background A risk assessment model for predicting the risk of haemolytic disease of the
fetus and newborn (HDFN) in future pregnancies following the transfusion of Rh (D)‐positive …

Rate of D‐alloimmunization in trauma does not depend on the number of RhD‐positive units transfused: the BEST collaborative study

JN Seheult, J Callum, M Delaney, R Drake… - …, 2022 - Wiley Online Library
Background Evidence indicates the life‐saving benefits of early blood product transfusion in
severe trauma resuscitation. Many of these products will be RhD‐positive, so understanding …

Perception of risk in massive transfusion as it relates to fetal outcomes: a survey of surgeons and nurses at one American trauma center

R Uhlich, P Hu, M Yazer, JO Jansen, P Patrician… - …, 2021 - Wiley Online Library
Background The use of blood products early in the resuscitation of bleeding trauma patients
is widely accepted, but made difficult by limited supplies of D− red blood cell (RBC) …

Implementation of Low Titer Whole Blood for French overseas operations: O positive or negative products in massive hemorrhage?

C Martinaud, E Fleuriot, P Pasquier - Transfusion Clinique et Biologique, 2022 - Elsevier
Massive hemorrhage is the leading preventable cause of death during military operations.
During these operations, the delay between initial treatment and arrival at a surgical facility …

Another piece of the hemolytic disease of the fetus and newborn puzzle after RhD-positive transfusion in trauma resuscitation: the proportion of pregnant women who …

MH Yazer, SP Emery, DJ Triulzi, P Spinella… - Trauma Surgery & …, 2024 - tsaco.bmj.com
Background After the transfusion of RhD-positive red blood cell (RBC)-containing products
to an RhD-negative woman of childbearing potential (WCP) during trauma resuscitation …

Use of low-titer O-positive whole blood in female trauma patients: a literature review, qualitative multidisciplinary analysis of risk/benefit, and guidelines for its use as a …

TW Clements, JM Van Gent, N Menon… - Journal of the …, 2023 - journals.lww.com
Background: Whole blood transfusion is associated with benefits including improved
survival, coagulopathy, and decreased transfusion requirements. The majority of whole …

Making every drop count: reducing wastage of a novel blood component for transfusion of trauma patients

J McCullagh, N Proudlove, H Tucker… - BMJ Open …, 2021 - bmjopenquality.bmj.com
Recent research demonstrates that transfusing whole blood (WB= red blood cells (RBC)+
plasma+ platelets) rather than just RBC (which is current National Health Service (NHS) …