[HTML][HTML] Persistence of human parvovirus B19 in multipotent mesenchymal stromal cells expressing the erythrocyte P antigen: implications for transplantation

M Sundin, A Lindblom, C Örvell, AJ Barrett… - Biology of Blood and …, 2008 - Elsevier
Multipotent mesenchymal stromal cells (MSCs) are used to improve the outcome of
hematopoietic stem cell transplantation (HCST) and in regenerative medicine. MSCs may …

Non-Permissive Parvovirus B19 Infection: A Reservoir and Questionable Safety Concern in Mesenchymal Stem Cells

G Bua, P Marrazzo, E Manaresi, C Gamberini… - International Journal of …, 2023 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) are multipotent cells with differentiation,
immunoregulatory and regenerative properties. Because of these features, they represent …

Ex Vivo-Generated CD36+ Erythroid Progenitors Are Highly Permissive to Human Parvovirus B19 Replication

S Wong, N Zhi, C Filippone, K Keyvanfar… - Journal of …, 2008 - Am Soc Microbiol
The pathogenic parvovirus B19 (B19V) has an extreme tropism for human erythroid
progenitor cells. In vitro, only a few erythroid leukemic cell lines (JK-1 and KU812Ep6) or …

Susceptibility of human erythropoietic cells to B19 parvovirus in vitro increases with differentiation

T Takahashi, K Ozawa, K Takahashi, S Asano… - 1990 - ashpublications.org
B19 human parvovirus is the etiologic agent of transient aplastic crisis. To better understand
B19 virus-induced hematopoietic suppression, we studied the host cell range of the virus …

Parvovirus B19 infection in human bone marrow mesenchymal stem cells affects gene expression of IL-6 and TNF-α and also affects hematopoietic stem cells …

M Behzadi Fard, S Kaviani, A Atashi - Indian Journal of Hematology and …, 2019 - Springer
Abstract Parvovirus B19 (B19V) has been known to induce transient erythroid aplasia,
cytopenia and aplastic anemia. This virus persists in bone marrow mesenchymal stem cells …

Parvovirus B19 in the context of hematopoietic stem cell transplantation: evaluating cell donors and recipients

BE Gama, VE Emmel, M Oliveira-Silva… - Transplantation …, 2017 - journals.lww.com
Background Parvovirus B19 (B19V) is a common human pathogen, member of the family
Parvoviridae. Typically, B19V has been found to infect erythroid progenitors and cause …

Autologous peripheral blood progenitor cells are a potential source of parvovirus B19 infection

DM Arnold, PB Neame, RM Meyer… - …, 2005 - Wiley Online Library
BACKGROUND: Parvovirus B19 is a cause of delayed red blood cell (RBC) engraftment
after marrow transplantation (BMT). The diagnosis of parvovirus infection requires serologic …

Role of erythropoietin receptor signaling in parvovirus B19 replication in human erythroid progenitor cells

AY Chen, W Guan, S Lou, Z Liu, S Kleiboeker… - Journal of …, 2010 - Am Soc Microbiol
ABSTRACT Parvovirus B19 (B19V) infection is highly restricted to human erythroid
progenitor cells. Although previous studies have led to the theory that the basis of this …

Parvovirus B19-induced perturbation of human megakaryocytopoiesis in vitro

A Srivastava, E Bruno, R Briddell, R Cooper… - 1990 - ashpublications.org
Parvovirus B19 infection leads to transient aplastic crises in individuals with chronic
hemolytic anemias or immunodeficiency states. An additional unexplained sequela of B19 …

Productive infection of in vitro generated haemopoietic progenitor cells from normal human adult peripheral blood with parvovirus B19: studies by morphology …

S Serke, TF Schwarz, H Baurmann… - British journal of …, 1991 - Wiley Online Library
Parvovirus B19 exerts a highly selective cytopathic effect on erythroid progenitor cells.
Studies so far on the pathogenesis of B19‐infection have been performed using bone …