Nuclear export of messenger RNA
J Katahira - Genes, 2015 - mdpi.com
Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …
Roles of the TREX complex in nuclear export of mRNA
J Katahira, Y Yoneda - RNA biology, 2009 - Taylor & Francis
Recent studies have established that nuclear export of mRNAs is functionally coupled to
different steps in gene expression processes, such as transcription, splicing, 3'-end …
different steps in gene expression processes, such as transcription, splicing, 3'-end …
Two closely related human nuclear export factors utilize entirely distinct export pathways
Nuclear mRNA export mediated by the human protein TAP requires a carboxy-terminal
domain that directly interacts with components of the nuclear pore complex. Here we …
domain that directly interacts with components of the nuclear pore complex. Here we …
The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
Messenger RNAs are exported from the nucleus as large ribonucleoprotein complexes
(mRNPs). To date, proteins implicated in this process include TAP/Mex67p and RAE1/Gle2p …
(mRNPs). To date, proteins implicated in this process include TAP/Mex67p and RAE1/Gle2p …
RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex
L Lévesque, B Guzik, T Guan, J Coyle, BE Black… - Journal of Biological …, 2001 - ASBMB
Nuclear export of ribonucleoprotein complexes requires cis-acting signals and recognition
by receptors that mediate translocation through the nuclear pore complex. Translocation is …
by receptors that mediate translocation through the nuclear pore complex. Translocation is …
The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences
The constitutive transport element (CTE) encoded by simian type D retroviruses directs
unspliced viral RNAs into a nuclear export pathway that is congruent with the pathway used …
unspliced viral RNAs into a nuclear export pathway that is congruent with the pathway used …
Polyadenylation and nuclear export of mRNAs
M Stewart - Journal of Biological Chemistry, 2019 - ASBMB
In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …
enables mRNA modifications such as capping, splicing, and polyadenylation. These …
Nuclear mRNA export: insights from virology
BR Cullen - Trends in biochemical sciences, 2003 - cell.com
To maximize the production of progeny virions, several viruses have evolved mechanisms
that promote the selective nuclear export of viral mRNA transcripts while, in some cases …
that promote the selective nuclear export of viral mRNA transcripts while, in some cases …
The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function
The human Tap protein mediates the sequence-specific nuclear export of RNAs containing
the constitutive transport element and is likely also critical for general mRNA export. Here …
the constitutive transport element and is likely also critical for general mRNA export. Here …
Nucleocytoplasmic transport: cargo trafficking across the border
K Weis - Current opinion in cell biology, 2002 - Elsevier
Transport of macromolecules between the cytoplasm and the nucleus is mediated by at least
three different classes of soluble transport receptors, members of the importin-β protein …
three different classes of soluble transport receptors, members of the importin-β protein …