Quantitative third-harmonic generation imaging of mouse visual cortex areas reveals correlations between functional maps and structural substrates
The structure of brain regions is assumed to correlate with their function, but there are very
few instances in which the relationship has been demonstrated in the live brain. This is due …
few instances in which the relationship has been demonstrated in the live brain. This is due …
Quantitative comparison of 3D third harmonic generation and fluorescence microscopy images
Third harmonic generation (THG) microscopy is a label‐free imaging technique that shows
great potential for rapid pathology of brain tissue during brain tumor surgery. However, the …
great potential for rapid pathology of brain tissue during brain tumor surgery. However, the …
Label-free live brain imaging and targeted patching with third-harmonic generation microscopy
The ability to visualize neurons inside living brain tissue is a fundamental requirement in
neuroscience and neurosurgery. Especially the development of a noninvasive probe of …
neuroscience and neurosurgery. Especially the development of a noninvasive probe of …
Dark-field third-harmonic imaging
Coherent cancellation of third-harmonic generation (THG) in a tightly focused laser beam is
shown to enable a label-free imaging of individual neurons in representative brain tissues …
shown to enable a label-free imaging of individual neurons in representative brain tissues …
A Method to Measure Myeloarchitecture of the Murine Cerebral Cortex in vivo and ex vivo by Intrinsic Third-Harmonic Generation
MJ Redlich, H Lim - Frontiers in neuroanatomy, 2019 - frontiersin.org
A new label-free method is presented for measuring myeloarchitecture of the murine
cerebral cortex in vivo and ex vivo. Growing evidence suggests that cortical myelination …
cerebral cortex in vivo and ex vivo. Growing evidence suggests that cortical myelination …
Endogenous SHG and 2PEF coherence imaging of substructures in neurons in 3D
C Macias-Romero, C Teulon, M Didier, S Roke - Optics Express, 2019 - opg.optica.org
Neuronal morphology, long-distance transport and signalling critically depend on the
organization of microtubules in the cytoskeleton. Second harmonic generation (SHG) …
organization of microtubules in the cytoskeleton. Second harmonic generation (SHG) …
Harmonic generation microscopy 2.0: new tricks empowering intravital imaging for neuroscience
H Lim - Frontiers in Molecular Biosciences, 2019 - frontiersin.org
Optical harmonic generation, eg, second-(SHG) and third-harmonic generation (THG),
provides intrinsic contrasts for three-dimensional intravital microscopy. Contrary to two …
provides intrinsic contrasts for three-dimensional intravital microscopy. Contrary to two …
Third harmonic generation imaging for fast, label-free pathology of human brain tumors
NV Kuzmin, P Wesseling, PCW Hamer… - Biomedical optics …, 2016 - opg.optica.org
In brain tumor surgery, recognition of tumor boundaries is key. However, intraoperative
assessment of tumor boundaries by the neurosurgeon is difficult. Therefore, there is an …
assessment of tumor boundaries by the neurosurgeon is difficult. Therefore, there is an …
[HTML][HTML] Adaptive optical third-harmonic generation microscopy for in vivo imaging of tissues
Third-harmonic generation microscopy is a powerful label-free nonlinear imaging technique,
providing essential information about structural characteristics of cells and tissues without …
providing essential information about structural characteristics of cells and tissues without …
Label-free assessment of hemodynamics in individual cortical brain vessels using third harmonic generation microscopy
We show that third harmonic generation (THG) microscopy using a 1-MHz train of 1,300-nm
femtosecond duration laser pulses enabled visualization of the structure and quantification …
femtosecond duration laser pulses enabled visualization of the structure and quantification …