[HTML][HTML] NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration

T Ku, B Li, R Gao, Y Zhang, W Yan, X Ji, G Li… - Particle and fibre …, 2017 - Springer
Abstract Background PM 2.5 (particulate matter≤ 2.5 μm) is one of the leading
environmental risk factors for the global burden of disease. Whereas increasing evidence …

Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route

C Liang, Y Jiang, T Zhang, Y Ji, Y Zhang, Y Sun… - Science of The Total …, 2023 - Elsevier
Atmospheric particulate matter (PM), a ubiquitous air pollutant, is the leading environmental
risk factor for mortality worldwide. Experimental and epidemiological studies consistently …

Recent advances in understanding the mechanisms of PM2. 5-mediated neurodegenerative diseases

X Zhu, X Ji, Y Shou, Y Huang, Y Hu, H Wang - Toxicology Letters, 2020 - Elsevier
PM 2.5 particles are widely believed to be associated with respiratory and cardiovascular
diseases. However, recent studies have reported that PM 2.5 may be associated with …

Ambient PM2. 5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation

Y Shou, X Zhu, D Zhu, H Yin, Y Shi, M Chen, L Lu… - Toxicology letters, 2020 - Elsevier
Abstract Fine particulate matter 2.5 (PM 2.5), one of the main components of air pollutants,
seriously threatens human health. Possible neuronal dysfunction induced by PM 2.5 has …

Neurotoxicity of the air-borne particles: from molecular events to human diseases

F Liu, C Liu, Y Liu, J Wang, Y Wang, B Yan - Journal of Hazardous Materials, 2023 - Elsevier
Exposure to PM 2.5 is associated with an increased incidence of CNS diseases in humans,
as confirmed by numerous epidemiological studies. Animal models have demonstrated that …

[HTML][HTML] Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model

SH Lee, YH Chen, CC Chien, YH Yan, HC Chen… - PLoS …, 2021 - journals.plos.org
Although numerous epidemiological studies revealed an association between ambient fine
particulate matter (PM2. 5) exposure and Alzheimer's disease (AD), the PM2. 5-induced …

Knockdown of long non-coding RNA AL049437 mitigates MPP+-induced neuronal injury in SH-SY5Y cells via the microRNA-205-5p/MAPK1 axis

L Zhang, J Wang, Q Liu, Z Xiao, Q Dai - Neurotoxicology, 2020 - Elsevier
Abstract Background Long noncoding RNAs (lncRNAs) have been defined as critical
regulators of various human diseases. However, the functions of lncRNAs in Parkinson's …

[HTML][HTML] Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats

HC Chuang, HC Chen, PJ Chai, HT Liao… - Particle and Fibre …, 2020 - Springer
Background Epidemiological evidence has linked fine particulate matter (PM 2.5) to
neurodegenerative diseases; however, the toxicological evidence remains unclear. The …

Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase‐mediated glutamate generation

F Liu, Y Huang, F Zhang, Q Chen, B Wu… - Journal of …, 2015 - Wiley Online Library
Exposure to atmospheric particulate matter PM 2.5 (aerodynamic diameter≤ 2.5 μm) has
been epidemiologically associated with respiratory illnesses. However, recent data have …

Possible association between PM2. 5 and neurodegenerative diseases: A systematic review

A Cristaldi, M Fiore, GO Conti, E Pulvirenti… - Environmental …, 2022 - Elsevier
Air pollution is one of the most serious environmental problems that afflict our planet and
one of the greatest risk factors for human health. In particular, PM 2.5 is able to cross the …