PM2. 5 exposure aggravates oligomeric amyloid beta-induced neuronal injury and promotes NLRP3 inflammasome activation in an in vitro model of Alzheimer's …

BR Wang, JQ Shi, NN Ge, Z Ou, YY Tian… - Journal of …, 2018 - Springer
Background Numerous studies suggested that PM2. 5 exposure was associated with
increased risk of Alzheimer's disease (AD). But the precise mechanisms by which PM2. 5 …

Redox/methylation mediated abnormal DNA methylation as regulators of ambient fine particulate matter-induced neurodevelopment related impairment in human …

H Wei, F Liang, G Meng, Z Nie, R Zhou, W Cheng… - Scientific Reports, 2016 - nature.com
Abstract Fine particulate matter (PM2. 5) has been implicated as a risk factor for
neurodevelopmental disorders including autism in children. However, the underlying …

miR-124-3p is a chronic regulator of gene expression after brain injury

N Vuokila, K Lukasiuk, AM Bot, EA van Vliet… - Cellular and molecular …, 2018 - Springer
Traumatic brain injury (TBI) initiates molecular and cellular pathologies that underlie post-
injury morbidities, including hippocampus-related memory decline and epileptogenesis …

Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors

X Ji, R Liu, J Guo, Y Li, W Cheng, Y Pang… - Science of The Total …, 2022 - Elsevier
Growing evidence has indicated that air pollution is associated with depression, and
damage of olfactory bulb (OB) is regarded as an early marker for depression. However, the …

PM2. 5 deregulated microRNA and inflammatory microenvironment in lung injury

G Liu, Y Li, J Zhou, J Xu, B Yang - Environmental Toxicology and …, 2022 - Elsevier
PM2. 5 negatively affects human health, particularly lung injury. However, the role of PM2. 5-
regulated miRNAs in lung injury remains unknown. MiRNA array results showed mmu-miR …

PM2.5 induces inflammatory responses via oxidative stress-mediated mitophagy in human bronchial epithelial cells

X Zhai, J Wang, J Sun, L Xin - Toxicology Research, 2022 - academic.oup.com
Background Fine particulate matter (PM2. 5) is a ubiquitous air pollutant, and it has been
reported to be closely associated with lung inflammatory injury. In this study, the potential …

Overexpression of miR‐138‐5p suppresses MnCl2‐induced autophagy by targeting SIRT1 in SH‐SY5Y cells

J Ma, Y Zhang, H Ji, L Chen, T Chen… - Environmental …, 2019 - Wiley Online Library
The mechanism of manganism caused by manganese (Mn), an important environmental risk
factor for Parkinson's disease, is still unclear. Recent evidence suggested that autophagy …

miR-124-3p attenuates MPP+-induced neuronal injury by targeting STAT3 in SH-SY5Y cells

L Geng, W Liu, Y Chen - Experimental Biology and Medicine, 2017 - journals.sagepub.com
Ample evidence has demonstrated the involvement of microRNAs in Parkinson's disease
pathogenesis. miR-124-3p was reported to be able to improve neural functional recovery …

The underlying mechanism of PM2. 5-induced ischemic stroke

Z Chen, P Liu, X Xia, L Wang, X Li - Environmental Pollution, 2022 - Elsevier
Under the background of global industrialization, PM 2.5 has become the fourth-leading risk
factor for ischemic stroke worldwide, according to the 2019 GBD estimates. This highlights …

Associations of short-term exposure to fine particulate matter with neural damage biomarkers: a panel study of healthy retired adults

J Song, R Qu, B Sun, R Chen, H Kan, Z An… - Environmental …, 2021 - ACS Publications
Exposure to fine particulate matter (PM2. 5) is associated with various adverse health
effects, such as respiratory and cardiovascular diseases. This study aimed to evaluate the …