Autism spectrum disorders (ASD) are highly disabling psychiatric disorders. Despite a strong
genetic etiology, there are no efficient therapeutic interventions that target the core …

Extensive health studies had declared that exposure to particulate matter (PM) was closely
associated with neurodegenerative diseases, ie Parkinson's disease (PD). Our aim was to …

To study central nervous system airborne PM related subchronic toxicity, SD male rats were
exposed for eight weeks to either coarse (32 μg/m 3), fine (178 μg/m 3) or ultrafine (107 …

Air pollutants have serious health effects on human beings. The 2010 Global Burden of
Disease study reports that each year, ambient particulate matter (PM2. 5, particles with …

Mitochondrial dysfunction is one of the major contributors to neurodegenerative disorders
including Parkinson disease. The mitochondrial permeability transition pore is a protein …

Worsening air pollution is a serious threat to public health in many urban and heavily
industrialized areas. Particle size and chemical composition are well known determinants of …

Objectives Exposure to airborne particle (PM2. 5) is a risk factor for intracranial
atherosclerosis (ICA). Because of the established role of systemic inflammation and …

Many epidemiological investigations have consistently demonstrated the immunotoxicity of
fine particulate matter (PM 2.5), but the underlying molecular mechanism remains unclear …

Exposure to particulate matter (PM) has been associated with a range of health impacts,
including neurological abnormalities that affect neurodevelopment, neuroplasticity, and …

Activation of microglia resulting in exacerbated inflammation expression plays an important
role in degeneration of dopaminergic (DA) neurons in the pathogenesis of Parkinson's …