Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …

NLRP3 inflammasome is a key mediator in ischemic stroke-induced neuroinflammation and
subsequent brain injury. Our previous study demonstrated the potent activity of Pien-Tze …

The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral
ischemic injury, and autophagy is related to activation of the inflammasome under oxidative …

Background Idebenone is a well-appreciated mitochondrial protectant while the
mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) …

Background The NLRP3 inflammasome is a multiprotein complex that regulates the innate
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …

Background Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial factor in
mediating inflammatory responses after cerebral ischemia/reperfusion (I/R), but the cellular …

Recent evidence suggests that Nod-like receptor protein-3 (NLRP3) inflammasome is a key
mediator of inflammatory response and can induce the activation of apoptosis signaling …

Ischemic stroke is a devastating disease with long-term disability. However, the
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …

The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral
ischemia. Autophagy may cause microglial inflammatory response or stimulate microglial …

NLRP6 inflammasome, one of the important intracellular innate immune sensors, has been
shown to regulate immune responses. However, its roles in the intracerebral hemorrhage …