[HTML][HTML] Salidroside inhibits NLRP3 inflammasome activation and apoptosis in microglia induced by cerebral ischemia/reperfusion injury by inhibiting the TLR4/NF-κB …
J Liu, W Ma, CH Zang, GD Wang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …
inflammasome is an important mediator of neuroinflammatory responses that regulates …
[HTML][HTML] Pien-Tze-Huang, a Chinese patent formula, attenuates NLRP3 inflammasome-related neuroinflammation by enhancing autophagy via the AMPK/mTOR/ULK1 …
Z Huang, X Zhou, X Zhang, L Huang, Y Sun… - Biomedicine & …, 2021 - Elsevier
NLRP3 inflammasome is a key mediator in ischemic stroke-induced neuroinflammation and
subsequent brain injury. Our previous study demonstrated the potent activity of Pien-Tze …
subsequent brain injury. Our previous study demonstrated the potent activity of Pien-Tze …
Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy
Y Wang, C Meng, J Zhang, J Wu, J Zhao - International …, 2019 - Elsevier
The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral
ischemic injury, and autophagy is related to activation of the inflammasome under oxidative …
ischemic injury, and autophagy is related to activation of the inflammasome under oxidative …
Idebenone attenuates cerebral inflammatory injury in ischemia and reperfusion via dampening NLRP3 inflammasome activity
J Peng, H Wang, Z Gong, X Li, L He, Q Shen, J Pan… - Molecular …, 2020 - Elsevier
Background Idebenone is a well-appreciated mitochondrial protectant while the
mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) …
mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) …
Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats
J Li, H Xu, S Nie, Y Peng, LF Fan, Z Wang… - Journal of …, 2017 - Springer
Background The NLRP3 inflammasome is a multiprotein complex that regulates the innate
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …
Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
Z Gong, J Pan, Q Shen, M Li, Y Peng - Journal of neuroinflammation, 2018 - Springer
Background Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial factor in
mediating inflammatory responses after cerebral ischemia/reperfusion (I/R), but the cellular …
mediating inflammatory responses after cerebral ischemia/reperfusion (I/R), but the cellular …
Anfibatide alleviates inflammation and apoptosis via inhibiting NF-kappaB/NLRP3 axis in ischemic stroke
R Li, M Si, HY Jia, Z Ma, XW Li, XY Li, XR Dai… - European Journal of …, 2022 - Elsevier
Recent evidence suggests that Nod-like receptor protein-3 (NLRP3) inflammasome is a key
mediator of inflammatory response and can induce the activation of apoptosis signaling …
mediator of inflammatory response and can induce the activation of apoptosis signaling …
Meisoindigo protects against focal cerebral ischemia-reperfusion injury by inhibiting NLRP3 inflammasome activation and regulating microglia/macrophage …
Y Ye, T Jin, X Zhang, Z Zeng, B Ye, J Wang… - Frontiers in cellular …, 2019 - frontiersin.org
Ischemic stroke is a devastating disease with long-term disability. However, the
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …
Geniposide inhibits NLRP3 inflammasome activation via autophagy in BV-2 microglial cells exposed to oxygen–glucose deprivation/reoxygenation
C Fu, X Zhang, Y Lu, F Wang, Z Xu, S Liu… - International …, 2020 - Elsevier
The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral
ischemia. Autophagy may cause microglial inflammatory response or stimulate microglial …
ischemia. Autophagy may cause microglial inflammatory response or stimulate microglial …
NLRP6 inflammasome ameliorates brain injury after intracerebral hemorrhage
PF Wang, ZG Li, Y Zhang, XH Ju, XW Liu… - Frontiers in Cellular …, 2017 - frontiersin.org
NLRP6 inflammasome, one of the important intracellular innate immune sensors, has been
shown to regulate immune responses. However, its roles in the intracerebral hemorrhage …
shown to regulate immune responses. However, its roles in the intracerebral hemorrhage …
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