O2/3 exposure inhibits cell progression affecting cyclin B1/cdk1 activity in SK‐N‐SH while induces apoptosis in SK‐N‐DZ neuroblastoma cells
A Cannizzaro, CV Falzacappa… - Journal of cellular …, 2007 - Wiley Online Library
In search for innovative therapeutic agents for children neuroblastoma, the oxygen therapy
could be considered an alternative anti‐tumoral treatment. Given the physiochemical …
could be considered an alternative anti‐tumoral treatment. Given the physiochemical …
In vitro CO2-induced ROS production impairs cell cycle in SH-SY5Y neuroblastoma cells
AS Montalto, M Curro, T Russo, G Visalli… - Pediatric surgery …, 2013 - Springer
Purpose We evaluated in vitro the role of CO 2-induced oxidative stress on the expression of
proteins involved in cell-cycle regulation of neuroblastoma cells. Methods SH-SY5Y cells …
proteins involved in cell-cycle regulation of neuroblastoma cells. Methods SH-SY5Y cells …
Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27Kip1 Upregulation
S Gopinath, RR Malla, CS Gondi, K Alapati, D Fassett… - PloS one, 2010 - journals.plos.org
Background Cathepsin B and urokinase plasminogen activator receptor (uPAR) are both
known to be overexpressed in gliomas. Our previous work and that of others strongly …
known to be overexpressed in gliomas. Our previous work and that of others strongly …
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma
JA Rader, MR Russell, LS Hart, MS Nakazawa… - Clinical cancer …, 2013 - AACR
Purpose: Neuroblastoma is a pediatric cancer that continues to exact significant morbidity
and mortality. Recently, a number of cell-cycle proteins, particularly those within the Cyclin …
and mortality. Recently, a number of cell-cycle proteins, particularly those within the Cyclin …
Retracted: CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells
Y Cao, X Li, S Kong, S Shang… - Journal of cellular and …, 2020 - Wiley Online Library
In adults, glioma is the most commonly occurring and invasive brain tumour. For malignant
gliomas, the current advanced chemotherapy includes TMZ (temozolomide). However, a …
gliomas, the current advanced chemotherapy includes TMZ (temozolomide). However, a …
GSK3β-dependent cyclin D1 and cyclin E1 degradation is indispensable for NVP-BEZ235 induced G0/G1 arrest in neuroblastoma cells
SL Liu, Z Liu, LD Zhang, HQ Zhu, JH Guo, M Zhao… - Cell Cycle, 2017 - Taylor & Francis
Cyclin D1 and cyclin E1, as vital regulatory factors of G1-S phase cell cycle progression, are
frequently constitutive expressed and associated with pathogenesis and tumorigenesis in …
frequently constitutive expressed and associated with pathogenesis and tumorigenesis in …
Roles of cyclin-dependent kinase 4 and p53 in neuronal cell death induced by doxorubicin on cerebellar granule neurons in mouse
Y Otsuka, T Tanaka, D Uchida, Y Noguchi, N Saeki… - Neuroscience …, 2004 - Elsevier
Cell cycle regulators such as cyclin-dependent kinases (Cdks) and their inhibitors (Ckis)
have been reported to be involved in neuronal cell death (NCD) induced by a variety of …
have been reported to be involved in neuronal cell death (NCD) induced by a variety of …
Involvement of reactive oxygen species in 2-methoxyestradiol-induced apoptosis in human neuroblastoma cells
Q Zhang, Y Ma, YF Cheng, WJ Li, Z Zhang, S Chen - Cancer letters, 2011 - Elsevier
Neuroblastoma is the most common extra-cranial solid tumor in children. Despite advances
in the treatment of childhood cancer, outcomes for children with advanced-stage …
in the treatment of childhood cancer, outcomes for children with advanced-stage …
Staurosporine-induced growth inhibition of glioma cells is accompanied by altered expression of cyclins, CDKs and CDK inhibitors
MN Harmalkar, NV Shirsat - Neurochemical research, 2006 - Springer
Staurosporine was found to bring about complete growth inhibition of human glioma cell
lines. U87 MG cells were arrested in S phase while U373 MG cells in G2/M phase on …
lines. U87 MG cells were arrested in S phase while U373 MG cells in G2/M phase on …
Induction of G1 arrest in glioma cells by T11TS is associated with upregulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1 and 3)
In our laboratory, a novel therapeutic probe, T11TS, a membrane glycoprotein, was isolated
which had antineoplastic activity against experimental glioma. Development of a novel …
which had antineoplastic activity against experimental glioma. Development of a novel …