Aims The aims of this study were to determine whether chronic oestrogen withdrawal
influences the development of ischaemic preconditioning (IPC) in female hearts, to …

Aim: Ischaemic preconditioning (IPC) has been demonstrated to protect heart function and
viability, but has been predominantly studied in male animals. Methods: We studied a …

To study the cell signaling events leading to 17β-estradiol (E2)-induced acute
cardioprotection, we subjected isolated rat hearts to three 5-min cycles of 10 μM E2 before …

BACKGROUND: The protective effects of 17-beta estradiol (E2) on cardiac tissue during
ischemia/reperfusion (I/R) injury have not yet been fully elucidated. OBJECTIVE: To assess …

Gender seems to interfere with the cardioprotective effect of ischemic preconditioning (PreC)
and postconditioning (PostC); PreC-conferred protection is weaker or lost in female animals …

The goal of this study was to determine if an ischemic preconditioning (IPC) protocol
improved post–ischemic functional recovery of female mouse hearts. A previous study found …

The role of pacing postconditioning (PPC) in the heart protection against ischemia–
reperfusion injury is not completely understood. The aim of this study was to investigated if …

Whether cardioprotection by postconditioning (PostC) is gender dependent is not clear. We
studied the effect of PostC in terms of both infarct size (IS) and post-ischemic systolic …

Objective Using non-selective and selective protein kinase C (PKC) ε and δ isoform
inhibitors, we tested the hypothesis that the cardioprotective phenotype invoked by …

The role of physiologic estrogen levels (pg) on post-ischemic myocardial function was
studied in the isolated working rat heart without (n= 28, experiment No. 1) or with (n= 15 …