Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study

GG Van den Eynden, I Van der Auwera… - British journal of …, 2006 - nature.com
Recently, peritumoural (lympho) vascular invasion, assessed on haematoxylin–eosin (HE)-
stained slides, was added to the St Gallen criteria for adjuvant treatment of patients with …

Significance of pathological evaluation for lymphatic vessel invasion in invasive breast cancer

M Ito, T Moriya, T Ishida, S Usami, A Kasajima… - Breast cancer, 2007 - jstage.jst.go.jp
Background: Lymphatic vessel invasion (LVI) has been conventionally assessed on
hematoxylin-eosin (HE) stained sections, but this assessment tends to be subjective. The …

Objective assessment of lymphatic and blood vascular invasion in lymph node‐negative breast carcinoma: findings from a large case series with long‐term follow‐up

RAA Mohammed, SG Martin… - The Journal of …, 2011 - Wiley Online Library
In a previous study on a small series of breast cancers, we developed objective methods for
the assessment of vascular invasion (VI), using immunohistochemical staining. We found …

The role of lymphatic and blood vessel invasion in predicting survival and methods of detection in patients with primary operable breast cancer

FJA Gujam, JJ Going, J Edwards… - Critical reviews in …, 2014 - Elsevier
Lymphovascular invasion (LBVI) has long been recognized as an essential step of
metastases in patients with cancer. However, the process of invasion into lymphatic and …

Improved methods of detection of lymphovascular invasion demonstrate that it is the predominant method of vascular invasion in breast cancer and has important …

RAA Mohammed, SG Martin, MS Gill… - The American journal …, 2007 - journals.lww.com
The presence of vascular invasion (VI), encompassing both lymphovascular invasion (LVI)
and blood vascular invasion (BVI), in breast cancer has been found to be a poor prognostic …

Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications

RAA Mohammed, IO Ellis, S Elsheikh, EC Paish… - Breast cancer research …, 2009 - Springer
Controversy exists regarding the topography of lymph vessels in breast cancer, their
usefulness as prognostic factors, relationship with angiogenesis and whether active …

Prognostic significance of lymphovascular invasion diagnosed by lymphatic endothelium immunostaining in breast cancer patients

K Tezuka, N Onoda, T Takashima… - Oncology …, 2007 - spandidos-publications.com
Prognostic factors for breast cancer include axillary lymph node status, tumor size, histology,
nuclear grade, presence of estrogen and progesterone receptors, HER2/neu status, and …

Assessment of tumour vascularity as a prognostic factor in lymph node negative invasive breast cancer

AM Schor, M Van Hoef, SS Dhesi, A Howell… - European Journal of …, 1993 - Elsevier
The association between tumour vascularity and relapse was examined in 93 patients with
lymph node negative (LNN) invasive breast cancer. Factor VIII-related antibody was used to …

Impact of the prognostic value of vascular invasion, but not lymphatic invasion, of the primary tumor in patients with breast cancer

T Fujii, R Yajima, T Hirakata, T Miyamoto… - Anticancer …, 2014 - ar.iiarjournals.org
Background: The prognostic value of lymphovascular invasion (LVI) in patients with breast
cancer is unclear. Lymphatic invasion may mainly represent the selective affinity of breast …

Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer

CSM Williams, RD Leek, AM Robson… - The Journal of …, 2003 - Wiley Online Library
Early metastasis to lymph nodes is a frequent complication in human breast cancer.
However, the extent to which this depends on lymphangiogenesis or on invasion of existing …