Tumor mutation burden-assisted risk stratification for papillary thyroid cancer
Z Chen, W Wang, J Xu, Y Song, H Zhu, T Ma, M Ge… - Endocrine, 2022 - Springer
Purpose Although papillary thyroid cancer (PTC) has a low mortality rate, the rate of
recurrence remains relatively high. This study aims to develop a molecular signature to …
recurrence remains relatively high. This study aims to develop a molecular signature to …
The predictive value of coexisting BRAFV600E and TERT promoter mutations on poor outcomes and high tumour aggressiveness in papillary thyroid carcinoma: A …
B Chen, Y Shi, Y Xu, J Zhang - Clinical endocrinology, 2021 - Wiley Online Library
BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
Impact of BRAF V600E and TERT Promoter Mutations on Response to Therapy in Papillary Thyroid Cancer
T Trybek, A Walczyk, D Gąsior-Perczak, I Pałyga… - …, 2019 - academic.oup.com
In this study, we examined the relationship between coexisting BRAF V600E and TERT
promoter mutations in papillary thyroid cancer (PTC) and response to therapy. PTC cases …
promoter mutations in papillary thyroid cancer (PTC) and response to therapy. PTC cases …
BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence
Purpose To investigate the prognostic value of the BRAF V600E mutation and the recently
identified TERT promoter mutation chr5: 1,295,228 C> T (C228T), individually and in their …
identified TERT promoter mutation chr5: 1,295,228 C> T (C228T), individually and in their …
Effects of Coexistent BRAFV600E and TERT Promoter Mutations on Poor Clinical Outcomes in Papillary Thyroid Cancer: A Meta-Analysis
S Moon, YS Song, YA Kim, JA Lim, SW Cho, JH Moon… - Thyroid, 2017 - liebertpub.com
Background: The presence of a telomerase reverse transcriptase (TERT) promoter mutation
has been suggested as a potential prognostic marker for thyroid cancer, and a synergistic …
has been suggested as a potential prognostic marker for thyroid cancer, and a synergistic …
Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis
HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective …
J Huang, J Wang, J Xv, J Wang, G Wang… - Clinical and Experimental …, 2024 - Springer
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in
papillary thyroid carcinoma (PTC) remains controversial. We aimed to investigate the AF of …
papillary thyroid carcinoma (PTC) remains controversial. We aimed to investigate the AF of …
A six-genotype genetic prognostic model for papillary thyroid cancer
A unique prognostic role of the genetic duet of BRAF V600E and TERT promoter mutations
in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation …
in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation …
The coexistence of genetic mutations in thyroid carcinoma predicts histopathological factors associated with a poor prognosis: a systematic review and network meta …
L Zhao, L Wang, X Jia, X Hu, P Pang, S Zhao… - Frontiers in …, 2020 - frontiersin.org
Purpose Genetic mutations may play an important role in the progression and invasion of
thyroid carcinoma (TC), and their coexistence may result in mutational synergy. The …
thyroid carcinoma (TC), and their coexistence may result in mutational synergy. The …
A molecular approach combined with American Thyroid Association classification better stratifies recurrence risk of classic histology papillary thyroid cancer
Background Prognosis among patients with differentiated thyroid cancer is widely variable.
Better understanding of biologic subtypes is necessary to stratify patients and improve …
Better understanding of biologic subtypes is necessary to stratify patients and improve …
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- therapy in papillary thyroid cancer
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