Vinorelbine tartrate (Navelbine): drug profile and nursing implications of a new vinca alkaloid.
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Vinorelbine (Navelbine™) is i. semisynthetic vinca alkaloid devoid ot serious neurotoxicity.
When given weekly vinorelbine has documented activity against many tumors, including …

The majority of data available for vinorelbine are based upon iv administration of the drug.
Initial phase I studies of vinorelbine were performed in France, and the dose-limiting toxicity …

Vinorelbine (VNR) is a semi-synthetic vinca alkaloid (5′ nor-anhydro-vinblastine) that
differs from other vinca alkaloids by a modification of the catharantine moiety of the …

Vindesine (des-acetyl Vinblastine) is a synthetic derivative of vinblastine, and was produced
with the hope that it would have less neurotoxicity and hematopoietic toxicity than other …

Vinorelbine (NVB) is a new anticancer drug belonging to the vinca alkaloid family that shows
activity as a single‐agent treatment in advanced non‐small cell Jung cancer (NSCLC) …

OBJECTIVE: To review the chemistry, pharmacology, pharmacokinetics, clinical activity,
adverse effects, and dosage and administration guidelines for vinorelbine in the treatment of …

Vinorelbine (VNB), 5-nor-anhydrovinblastine, is a new semisynthetic vinca alkaloid with a
broad spectrum of antineoplastic activity both in vitro [1] and in vivo. Promising therapeutic …

Summary Vinorelbine (5′-noranhydrovinblastine) is a recently developed semisynthetic
anticancer drug which belongs to the Catharanthus alkaloid family. Its mechanism of action …

Purpose Better understanding of pharmacokinetics of oral vinorelbine (VNR) in children
would help predicting drug exposure and, beyond, clinical outcome. Here, we have …