[HTML][HTML] Exosomes and other extracellular vesicles in neural cells and neurodegenerative diseases

AM Janas, K Sapoń, T Janas, MHB Stowell… - Biochimica et Biophysica …, 2016 - Elsevier
The function of human nervous system is critically dependent on proper interneuronal
communication. Exosomes and other extracellular vesicles are emerging as a novel form of …

[HTML][HTML] Insights into the proteomic profiling of extracellular vesicles for the identification of early biomarkers of neurodegeneration

R Quiroz-Baez, K Hernández-Ortega… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) are involved in the development and progression of
neurodegenerative diseases, including Alzheimer's and Parkinson's disease. Moreover, EVs …

[HTML][HTML] Role of exosomes/microvesicles in the nervous system and use in emerging therapies

CPK Lai, XO Breakefield - Frontiers in physiology, 2012 - frontiersin.org
Extracellular membrane vesicles (EMVs) are nanometer sized vesicles, including exosomes
and microvesicles capable of transferring DNAs, mRNAs, microRNAs, non-coding RNAs …

[HTML][HTML] VAPB ER-aggregates, a possible new biomarker in ALS pathology

MPL Cadoni, ML Biggio, G Arru, G Secchi, N Orrù… - Cells, 2020 - mdpi.com
A point mutation (P56S) in the gene-encoding vesicle-associated membrane-protein-
associated protein B (VAPB) leads to an autosomal-dominant form of amyotrophic lateral …

Extracellular vesicles and exosome: insight from physiological regulatory perspectives

MY Waqas, MA Javid, MM Nazir, N Niaz… - Journal of physiology …, 2022 - Springer
The current study highlights prospective mechanisms of biogenesis of extracellular vesicles
(EVs) and potential involvement in cellular signaling and transport with great emphasis to …

[HTML][HTML] CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1) G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1

JM Silverman, D Christy, CC Shyu, KM Moon… - Journal of Biological …, 2019 - ASBMB
Extracellular vesicles (EVs) are secreted by myriad cells in culture and also by unicellular
organisms, and their identification in mammalian fluids suggests that EV release also occurs …

[HTML][HTML] Biomarkers for parkinsonian disorders in CNS-originating EVs: promise and challenges

S Dutta, S Hornung, HB Taha, G Bitan - Acta neuropathologica, 2023 - Springer
Extracellular vesicles (EVs), including exosomes, microvesicles, and oncosomes, are nano-
sized particles enclosed by a lipid bilayer. EVs are released by virtually all eukaryotic cells …

[HTML][HTML] Glia-derived extracellular vesicles: role in central nervous system communication in health and disease

C Pistono, N Bister, I Stanová, T Malm - Frontiers in cell and …, 2021 - frontiersin.org
Glial cells are crucial for the maintenance of correct neuronal functionality in a physiological
state and intervene to restore the equilibrium when environmental or pathological conditions …

[HTML][HTML] Role of glia-derived extracellular vesicles in neurodegenerative diseases

T Li, X Tan, S Li, M Al-Nusaif, W Le - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Extracellular vesicles (EVs), as nano-sized vesicles secreted by almost all cells, have been
recognized as the essential transmitter for cell-to-cell communication and participating in …

[HTML][HTML] Insight into the role of extracellular vesicles in lysosomal storage disorders

B Tancini, S Buratta, K Sagini, E Costanzi, F Delo… - Genes, 2019 - mdpi.com
Extracellular vesicles (EVs) have received increasing attention over the last two decades.
Initially, they were considered as just a garbage disposal tool; however, it has progressively …