Simple Summary Exosomes are biological nanoparticles recently recognized as intercellular
messengers. They contain a cargo of lipids, proteins, and RNA. They can transfer their …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive muscle paralysis determined by the degeneration of motoneurons in the motor …

Intercellular communication has recently been shown to occur via transfer of cargo loaded
within extracellular vesicles (EVs). Present within all biofluids of the body, EVs can contain …

Extracellular vesicles (EVs) are a subclass of biological nanoparticles secreted by most cell
types. Once secreted, EVs can travel long distances to deliver their content to target cells …

The abnormal deposition of proteins in brain tissue is a common feature of
neurodegenerative diseases (NDs) often accompanied by the spread of mutated proteins …

Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder which is
characterized by progressive degeneration of the motor system. Typically, the disease starts …

Neurodegenerative disorders are characterized by complex multifactorial pathogeneses,
thus posing a challenge for standard therapeutic approaches that tend to focus only on one …

Growing evidence indicates the role of exosomes in a variety of physiological pathways as
conveyors of biological materials from cell-to-cell. However the molecular mechanism (s) of …

Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …