A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor

A Gironell, J Kulisevsky, M Barbanoj… - Archives of …, 1999 - jamanetwork.com
Background New medication is needed to treat essential tremor. Preliminary evidence
suggests that gabapentin may be effective in the treatment of this disorder. Objective To …

Gabapentin for essential tremor: a multiple‐dose, double‐blind, placebo‐controlled trial

W Ondo, C Hunter, KD Vuong… - … : official journal of the …, 2000 - Wiley Online Library
Essential tremor (ET) is a common movement disorder that often becomes refractory to
conventional pharmacologic management. Open-label studies suggest that gabapentin is …

Double‐blind controlled trial of gabapentin in essential tremor

R Pahwa, K Lyons, JP Hubble, K Busenbark… - Movement …, 1998 - Wiley Online Library
Gabapentin has been reported to be effective for essential tremor (ET) based on open‐label
trials. We studied gabapentin (1800 mg/day) and placebo in a double‐blind crossover …

Gabapentin for parkinsonism: a double-blind, placebo-controlled, crossover trial

WL Olson, M Gruenthal, ME Mueller… - The American journal of …, 1997 - Elsevier
PURPOSE: Gabapentin is a recently available anticonvulsant whose mechanism of action
remains unknown. We suspected efficacy from serendipitous observations of gabapentin in …

Gabapentin in orthostatic tremor: results of a double-blind crossover with placebo in four patients

M Onofrj, A Thomas, C Paci, G D'Andreamatteo - Neurology, 1998 - AAN Enterprises
We treated four patients affected by orthostatic tremor (OT) with gabapentin in increasing
doses (300 to 2,400 mg/d). OT was evaluated with patients' self-monitoring scales, tremor …

A multicenter randomized crossover multiple-dose comparison study of arotinolol and propranolol in essential tremor

KS Lee, JS Kim, JW Kim, WY Lee, BS Jeon… - Parkinsonism & related …, 2003 - Elsevier
Background. A new medication is needed to treat essential tremor. Preliminary evidence
suggests that arotinolol may be effective in the treatment of this disorder. Objective. To study …

Efficacy and tolerability of pregabalin in essential tremor: a randomized, double-blind, placebo-controlled, crossover trial

JM Ferrara, C Kenney, AL Davidson, L Shinawi… - Journal of the …, 2009 - Elsevier
We performed a double-blind, crossover-design study to assess the tolerability and efficacy
of pregabalin (PGB) in patients with essential tremor (ET). Twenty patients (11 women; mean …

A New Twist for Stopping the Shakes?: Revisiting GABAergic Therapy for Essential Tremor

ED Louis - Archives of neurology, 1999 - jamanetwork.com
Aside from physiological tremor, essential tremor (ET) is by far the most common cause of
tremor in humans, affecting large numbers of individuals in every human popula-tion. 1 The …

Phenobarbital and propranolol in essential tremor: a double‐blind controlled clinical trial

A Baruzzi, G Procaccianti, P Martinelli, R Riva… - Neurology, 1983 - AAN Enterprises
In a double-blind study with Latin square design, phenobarbital (about 1.3 mg per kilogram),
propranolol (about 1.7 mg per kilogram), and placebo were given orally for 1 month to 12 …

Acute and chronic effects of propranolol and primidone in essential tremor

WC Koller, B Vetere-Overfield - Neurology, 1989 - AAN Enterprises
We studied the acute and chronic effects of propranolol and primidone in essential tremor by
administering long-acting propranolol (80 to 160 mg/d) and primidone (50 to 250 mg/d) to 50 …