Purpose The rates of early death (ED) and treatment-related mortality (TRM) are
unacceptably high in children undergoing intensive chemotherapy for acute myeloid …

Allogeneic bone marrow transplantation (BMT) may offer the only chance of cure for children
with acute myeloid leukemia (AML) in second complete remission (CR2) or with relapsed …

Since 1982, four consecutive studies on childhood acute myeloid leukaemia (AML)(namely
LAM-82,-87,-87M and-92) have been conducted in Italy by the Associazione Italiana di …

Abstract From 1989 to 1998, 341 children were included in the French multicentric LAME
(Leucémie Aiguë Myéloblastique Enfant) trials. A total of 309 children were registered in the …

Purpose To improve the prognosis in children with newly diagnosed acute myeloid leukemia
(AML) by introducing a dose-dense intensive chemotherapy regimen and an appropriate …

Overall survival (OS) of pediatric patients with acute myeloid leukemia (AML) increased in
recent decades. However, it remained unknown whether advances in first-line treatment …

Background The value of autologous bone marrow transplantation in the treatment of
children with acute myeloid leukemia (AML) is unknown. We compared autologous bone …

One hundred fifty-one children with acute myelogenous leukemia (AML) entered the
cooperative study BFM-78 between December 1978 and October 1982. The initial therapy …

Purpose: After present first-line therapies for childhood acute myeloid leukemia (AML),
nearly 40% of patients still relapse. The goals of this retrospective study were to determine …

A total of 1111 children with acute myeloblastic leukaemia (AML) were treated in four
consecutive Berlin–Frankfurt–Münster (BFM) studies from 1978 to 1998. The first …