Phenotyping C. elegans and neuronal cells in microengineered devices

RJ Lycke - 2012 - search.proquest.com
Phenotype denotes the observable traits or behaviors of any living subject such as cells,
animals, and humans. In the post-genomics era, the next major challenge in the biological …

Microfluidic Devices for Behavioral Analysis, Microscopy, and Neuronal Imaging in Caenorhabditis elegans

RC Lagoy, E Larsen, D Lawler, H White… - C. elegans: Methods …, 2022 - Springer
Microfluidic devices offer several advantages for C. elegans research, particularly for
presenting precise physical and chemical environments, immobilizing animals during …

Microfluidic Devices for Behavioral Analysis, Microscopy, and Neuronal Imaging in Caenorhabditis elegans

RC Lagoy, DR Albrecht - C. elegans: Methods and Applications, 2015 - Springer
Microfluidic devices offer several advantages for C. elegans research, particularly for
presenting precise physical and chemical environments, immobilizing animals during …

On-chip phenotypic screening and characterization of C. elegans enabled by microfluidics and image analysis methods

IC Cáceres Mendieta - 2013 - repository.gatech.edu
Since its introduction in 1960's, the model organism Caenorhabditis elegans has played a
crucial role towards scientific discoveries because of its relatively simple anatomy …

Microfluidics for the analysis of behavior, nerve regeneration, and neural cell biology in C. elegans

A Ben-Yakar, N Chronis, H Lu - Current opinion in neurobiology, 2009 - Elsevier
The nematode Caenorhabditis elegans is a widely adopted model organism for studying
various neurobiological processes at the molecular and cellular level in vivo. With a small …

Microfluidic devices for imaging and manipulation of C. elegans

AS Clark, J Huayta, KS Arulalan… - Micro and Nano Systems …, 2021 - Elsevier
The nematode Caenorhabditis elegans is a model organism widely used to study
development, neuroscience, disease modeling, and aging. Due to their small size …

Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans

D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

MC Letizia, M Cornaglia, R Trouillon… - Microsystems & …, 2018 - nature.com
The organism Caenorhabditis elegans is a performant model system for studying human
biological processes and diseases, but until now all phenome data are produced as …

Caenorhabditis elegans-on-a-chip: microfluidic platforms for high-resolution imaging and phenotyping

S Mondal, A Ben-Yakar - Organ-on-a-chip, 2020 - Elsevier
Caenorhabditis elegans is an attractive alternative animal model for identifying toxicological
phenotypes in vivo, studying the mode of action of drugs, and characterizing physiological …

Neuroscience research using small animals on a chip: from nematodes to zebrafish larvae

P Bansal, A Abraham, J Garg, EE Jung - BioChip Journal, 2021 - Springer
Implementation of microfluidic technology to study small animal models such as
Caenorhabditis elegans worms (soil-dwelling nematodes), Drosophila melanogaster (fruit …