Electron microscopy and immunohistochemical analysis clarified the phenotype of
macrophages that are not transformed into foam cells. It is suggested that cells having such …

Coronary artery walls in 18 autopsy cases of myocardial infarction, 18 cases of acute
coronary failure, 21 cases of violent death of presenile and senile subjects with age-specific …

The aim of this study was to reconstruct dynamic biological steps of human atherosclerosis
at different ages of life and, in particular, to clarify the role of the smooth muscle cells (SMCs) …

Background: Cholesterol expands in volume with crystallization that can lead to arterial wall
injury by perforating the intima and plaque cap. To elucidate the role of cholesterol crystals …

The development of arteriosclerosis results from diverse pathogenetic sources, and it is
conceivable, therefore, that the course of morphogenesis as well as the ultimate picture of …

This study was undertaken to investigate the expression of cytoskeletal proteins and the
ultrastructure of cells in normal intima and atheromatous plaque of human aorta. It has been …

Lesions produced in the rabbit aorta by cholesterol and cottonseed oil were studied with the
electron microscope. These lesions showed two main cell types: vacuolated cells containing …

Coronary atherosclerotic plaques were revealed by light microscopy in 12% of adolescents
and in 28% of young adults. All the plaques of adolescents and one-third of the plaques of …

The main components of the advanced atherosclerotic plaque are the necrotic cholesteryl
ester-rich core from which the disease process gets part of its name (the Greek stem “athero” …

The initial step in the process of atherosclerosis is supposed to be an increased penetration
of lipoprotein particles (especially LDL or Lp (a)) into the subendothelial space. It occurs …