Vasopressin deficiency and vasodilatory state in end-stage liver disease

G Wagener, G Kovalevskaya, M Minhaz, F Mattis… - Journal of cardiothoracic …, 2011 - Elsevier
OBJECTIVES:: Relative vasopressin deficiency, a contributor to vasodilatory septic shock,
also may be a cause of the vasodilatory state in liver disease. This study assessed …

Vasopressin‐induced changes in splanchnic blood flow and hepatic and portal venous pressures in liver resection

L Sand Bown, SE Ricksten, E Houltz… - Acta …, 2016 - Wiley Online Library
Background To minimize blood loss during hepatic surgery, various methods are used to
reduce pressure and flow within the hepato‐splanchnic circulation. In this study, the effect of …

Abnormal pressor response to vasopressin in patients with cirrhosis: evidence for impaired buffering mechanisms

R Moreau, A Hadengue, T Soupison, G Mechin… - Hepatology, 1990 - journals.lww.com
In patients with cirrhosis, vasopressin infusion induces sustained vasoconstriction and
elevation of arterial pressure. The vasopressor effect could be caused by impairment of …

Vasopressin deficiency contributes to the vasodilation of septic shock

DW Landry, HR Levin, EM Gallant, RC Ashton, S Seo… - Circulation, 1997 - Am Heart Assoc
Background The hypotension of septic shock is due to systemic vasodilation. On the basis of
a clinical observation, we investigated the possibility that a deficiency in vasopressin …

Clinical impact of vasopressin infusion on hemodynamics, liver and renal function in pediatric patients

N Jerath, H Frndova, BW McCrindle, R Gurofsky… - Intensive care …, 2008 - Springer
Objective To study effects of vasopressin on hemodynamic, clinical, and laboratory variables
in children with advanced vasodilatory shock. Design and setting Retrospective study in a …

[PDF][PDF] Vasopressin decreases portal vein pressure and flow in the native liver during liver transplantation

G Wagener, G Gubitosa, J Renz… - Liver …, 2008 - Wiley Online Library
Vasodilation due to impaired vascular tone is common in liver failure. Vasoconstrictor drugs
are almost always required during the anhepatic phase of a liver transplant to maintain …

The effects of vasopressin and its analogues on the liver and its disorders in the critically ill

P Asfar, P Radermacher, P Calès… - Current opinion in critical …, 2010 - journals.lww.com
The use of vasopressin and its synthetic analogues has shown beneficial effects in the
management of patients with cirrhosis, especially in the context of variceal bleeding, the …

Decreased vasopressin responsiveness in vasodilatory septic shock–like conditions

M Leone, WA Boyle - Critical care medicine, 2006 - journals.lww.com
Objective: To determine the effect of vasodilatory septic shock–like conditions on
vasoconstricting responses to vasopressin and norepinephrine in isolated resistance …

[PDF][PDF] Hyposensitivity to vasopressin in patients with hepatitis B–related cirrhosis during acute variceal hemorrhage

YT Tsai, FY Lee, HC Lin, SD Lee, HC Hsia, WJ Lin… - …, 1991 - Wiley Online Library
It has been suggested that vasopressin given during hemorrhage may be less effective than
when given during a stable state in a portal‐hypertensive rat model. This study was …

Treatment of portal hypertension with isosorbide dinitrate alone and in combination with vasopressin

R Hallemans, R Naeije, P Mols, C Melot… - Critical care …, 1983 - journals.lww.com
Experimental animal studies have suggested that certain vasodilators could minimize the
adverse cardiovascular effects of vasopressin. We investigated the hemo-dynamic effects of …