Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group
SC Reshmi, RC Harvey, KG Roberts… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk
subtype characterized by genomic alterations that activate cytokine receptor and kinase …
subtype characterized by genomic alterations that activate cytokine receptor and kinase …
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group
KG Roberts, SC Reshmi, RC Harvey… - Blood, The Journal …, 2018 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL; BCR-ABL1–like
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …
Ph-like acute lymphoblastic leukemia
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a newly
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
High frequency and poor outcome of Philadelphia chromosome–like acute lymphoblastic leukemia in adults
KG Roberts, Z Gu, D Payne-Turner… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …
risk subtype of childhood ALL characterized by kinase-activating alterations that are …
[HTML][HTML] Development and validation of a highly sensitive and specific gene expression classifier to prospectively screen and identify B-precursor acute lymphoblastic …
RC Harvey, H Kang, KG Roberts, IML Chen, SR Atlas… - Blood, 2013 - Elsevier
Using gene expression profiling, we and others identified a novel subgroup of B-precursor
acute lymphoblastic leukemia (B-ALL) with a gene expression signature similar to …
acute lymphoblastic leukemia (B-ALL) with a gene expression signature similar to …
[HTML][HTML] Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia
KM Bernt, SP Hunger - Frontiers in oncology, 2014 - frontiersin.org
The t (9; 22)(q34; q11) or Philadelphia chromosome creates a BCR–ABL1 fusion gene
encoding for a chimeric BCR–ABL1 protein. It is present in 3–4% of pediatric acute …
encoding for a chimeric BCR–ABL1 protein. It is present in 3–4% of pediatric acute …
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
J Zhang, CG Mullighan, RC Harvey… - Blood, The Journal …, 2011 - ashpublications.org
We sequenced 120 candidate genes in 187 high-risk childhood B-precursor acute
lymphoblastic leukemias, the largest pediatric cancer genome sequencing effort reported to …
lymphoblastic leukemias, the largest pediatric cancer genome sequencing effort reported to …
Philadelphia chromosome–like acute lymphoblastic leukemia
CH Pui, KG Roberts, JJ Yang, CG Mullighan - Clinical Lymphoma Myeloma …, 2017 - Elsevier
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a recently
described B-cell precursor ALL with a gene expression profile and a high frequency of IKZF1 …
described B-cell precursor ALL with a gene expression profile and a high frequency of IKZF1 …
[HTML][HTML] Philadelphia-like acute lymphoblastic leukemia is associated with minimal residual disease persistence and poor outcome. First report of the minimal residual …
Early recognition of Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) cases
could impact on the management and outcome of this subset of B-lineage ALL. In order to …
could impact on the management and outcome of this subset of B-lineage ALL. In order to …