Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches

R Singh, EJ Lehrer, S Ko, J Peterson, Y Lou… - Radiotherapy and …, 2020 - Elsevier
Background and purpose To analyze outcomes of non-small cell lung cancer (NSCLC)
patients with brain metastases harboring EGFR or ALK mutations and examine for …

[HTML][HTML] Recommended first-line management of asymptomatic brain metastases from EGFR mutant and ALK positive non-small cell lung cancer varies significantly …

CH Fong, N Meti, T Kruser, J Weiss, ZA Liu… - Journal of Thoracic …, 2023 - ncbi.nlm.nih.gov
Background The role for radiotherapy or surgery in the upfront management of brain
metastases (BrM) in epidermal growth factor receptor mutant (EGFRm) or anaplastic …

A neuro-oncologist's perspective on management of brain metastases in patients with EGFR mutant non-small cell lung cancer

T McGranahan, S Nagpal - Current Treatment Options in Oncology, 2017 - Springer
Opinion statement Management of non-small cell lung cancer (NSCLC) with brain
metastasis (BrM) has been revolutionized by identification of molecular subsets that have …

Impact of EGFR mutation and ALK rearrangement on the outcomes of non–small cell lung cancer patients with brain metastasis

SK Balasubramanian, M Sharma, VA Venur… - Neuro …, 2020 - academic.oup.com
Background The impact of activating alterations in non–small cell lung cancer
(NSCLC)(epidermal growth factor receptor [EGFR] mutation/anaplastic lymphoma kinase …

The optimal therapy strategy for epidermal growth factor receptor‐mutated non‐small cell lung cancer patients with brain metastasis: A real‐world study from Taiwan

WC Cheng, YC Shen, CR Chien, WC Liao… - Thoracic …, 2022 - Wiley Online Library
Background The treatment options for epidermal growth factor receptor (EGFR)‐mutated
non‐small cell lung cancer (NSCLC) with brain metastases (BMs) include EGFR‐tyrosine …

Treatment options for patients with brain metastases from EGFR/ALK-driven lung cancer

MK Doherty, GJ Korpanty, P Tomasini… - Radiotherapy and …, 2017 - Elsevier
Introduction Brain metastases in EGFR/ALK-driven NSCLC frequently pose treatment
dilemmas. Tyrosine kinase inhibitors (TKIs) can control extracranial disease, but …

Management of brain metastases in tyrosine kinase inhibitor–naïve epidermal growth factor receptor–mutant non–small-cell lung cancer: a retrospective multi …

WJ Magnuson, NH Lester-Coll, AJ Wu… - Journal of clinical …, 2017 - ascopubs.org
Purpose Stereotactic radiosurgery (SRS), whole-brain radiotherapy (WBRT), and epidermal
growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are treatment options for …

Does lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation?

TJC Wang, S Saad, YH Qureshi, A Jani… - Neuro …, 2015 - academic.oup.com
Background We investigated effects of genetic alterations in epidermal growth factor
receptor (EGFR), anaplastic lymphoma kinase (ALK), and Kirsten rat sarcoma viral …

EGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data

Y Fan, X Xu, C Xie - OncoTargets and therapy, 2014 - Taylor & Francis
Introduction Brain metastases are one of the leading causes of death from non-small-cell
lung cancer (NSCLC). The use of epidermal growth factor receptor (EGFR) tyrosine kinase …

Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non–small cell lung cancer treated with radiotherapy for …

KS Mak, JF Gainor, A Niemierko, KS Oh… - Neuro …, 2015 - academic.oup.com
Background We determined the impact of genetic alterations in EGFR, ALK, or KRAS on
survival after radiotherapy for brain metastases in non–small cell lung cancer (NSCLC) …