Nitric-oxide-donating NSAIDs as agents for cancer prevention
B Rigas, K Kashfi - Trends in Molecular Medicine, 2004 - cell.com
Nitric-oxide-donating nonsteroidal anti-inflammatory drugs (NO–NSAIDs), which consist of
an NSAID with an NO-donating moiety covalently attached to it, promise to contribute …
an NSAID with an NO-donating moiety covalently attached to it, promise to contribute …
Novel agents for cancer prevention based on nitric oxide
B Rigas - Biochemical Society Transactions, 2007 - portlandpress.com
NO (nitric oxide) biology has provided the impetus for the development of anticancer agents
based on their ability to release NO. NO-NSAIDs (NO-donating non-steroidal anti …
based on their ability to release NO. NO-NSAIDs (NO-donating non-steroidal anti …
NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property …
RK Yeh, J Chen, JL Williams, M Baluch… - Biochemical …, 2004 - Elsevier
The novel nitric oxide-donating nonsteroidal antiinflammatory drugs (NO-NSAIDs),
consisting of a traditional NSAID to which a NO releasing moiety is covalently attached, may …
consisting of a traditional NSAID to which a NO releasing moiety is covalently attached, may …
NO-donating NSAIDs and cancer: an overview with a note on whether NO is required for their action
B Rigas, JL Williams - Nitric Oxide, 2008 - Elsevier
Nitric oxide-donating nonsteroidal anti-inflammatory drugs (NO-NSAIDs) consist of a
conventional NSAID to which an NO-releasing moiety is attached covalently, often via a …
conventional NSAID to which an NO-releasing moiety is attached covalently, often via a …
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs …
JL Williams, S Borgo, I Hasan, E Castillo, F Traganos… - Cancer Research, 2001 - AACR
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs), consisting of a
known nonsteroidal anti-inflammatory drug (NSAID) and a nitric oxide (NO)-releasing group …
known nonsteroidal anti-inflammatory drug (NSAID) and a nitric oxide (NO)-releasing group …
Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect
The novel nitric oxide (NO)-donating nonsteroidal anti-inflammatory drugs (NO-NSAIDs),
which are safer than their NSAID counterparts, inhibit the growth of colon cancer cells with …
which are safer than their NSAID counterparts, inhibit the growth of colon cancer cells with …
Nitric oxide–releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets
CV Rao, BS Reddy, VE Steele, CX Wang, X Liu… - Molecular cancer …, 2006 - AACR
Nitric oxide–releasing nonsteroidal anti-inflammatory drugs (NO-NSAID) are promising
chemoprevention agents; unlike conventional NSAIDs, they seem free of appreciable …
chemoprevention agents; unlike conventional NSAIDs, they seem free of appreciable …
NO-releasing NSAIDs and colon cancer chemoprevention: a promising novel approach
B Rigas, JL Williams - International journal of oncology, 2002 - spandidos-publications.com
The chemoprevention of colon cancer, the second leading cause of cancer-related deaths in
the United States, has been pursued actively during the last two decades. Methodological …
the United States, has been pursued actively during the last two decades. Methodological …
NOSH–aspirin (NBS-1120), a novel nitric oxide-and hydrogen sulfide-releasing hybrid is a potent inhibitor of colon cancer cell growth in vitro and in a xenograft mouse …
M Chattopadhyay, R Kodela, KR Olson… - … and biophysical research …, 2012 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are prototypical anti-cancer agents.
However, their long-term use is associated with adverse gastrointestinal effects. Recognition …
However, their long-term use is associated with adverse gastrointestinal effects. Recognition …
Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation
TR Hundley, B Rigas - Journal of Pharmacology and Experimental …, 2006 - ASPET
Nitric oxide-donating aspirin (NO-aspirin), representing a new concept in the development of
more efficacious nonsteroidal anti-inflammatory drugs, consists of traditional aspirin bearing …
more efficacious nonsteroidal anti-inflammatory drugs, consists of traditional aspirin bearing …