Inflammation is part of the body's response to internal and external environmental stimuli
that normally eliminate the aggressor agent and restore the tissue physiology. However …

Nitric oxide (NO) acts as a key signalling mechanism in a number of cells and tissues in the
mammalian organism. Modulation of the biosynthesis of NO has emerged to be relevant to …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed drugs
worldwide owing to their anti-inflammatory, antipyretic and analgesic properties. However …

NO-donating aspirin (NO-ASA) is a potentially important chemopreventive agent against
cancer. Since positional isomerism affects strongly its potency in inhibiting colon cancer cell …

Nonsteroidal anti-inflammatory drugs (NSAID) have been highly effective in preventing
colon, urinary bladder, and skin cancer preclinically, and also in clinical trials of colon …

Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …

Purpose Previously, we reported in vitro observations suggesting that ibuprofen is an
effective non-prescription non-steroidal anti-inflammatory drug (NSAID) to reduce the …

Nonsteroidal anti-inflammatory drugs such as sulindac have shown promising antineoplastic
activity, although toxicity from cyclooxygenase (COX) inhibition and the suppression of …

Non-steroidal anti-inflammatory drugs (NSAIDs) including cyclooxygenase 2 (COX-2)
selective inhibitors, are potential agents for the chemoprevention of gastric cancer …

Nonsteroidal anti-inflammatory drugs (NSAID) display promising antineoplastic activity, but
toxicity resulting from cyclooxygenase (COX) inhibition limits their clinical use for …