Lupus anticoagulant testing using two parallel methods detects additional cases and predicts persistent positivity
DP Simmons, AZ Herskovits, EM Battinelli… - Clinical Chemistry and …, 2018 - degruyter.com
Background: Antiphospholipid antibody syndrome (APS) is characterized by laboratory
evidence of antiphospholipid antibodies (aPL)[eg lupus anticoagulant (LA), anticardiolipin …
evidence of antiphospholipid antibodies (aPL)[eg lupus anticoagulant (LA), anticardiolipin …
Routine Lupus Anticoagulant Sensitive aPTT Testing Can Prevent Unnecessary LA Testing
B Smit, F Hudig, JH Venhuizen… - Clinical and Applied …, 2023 - journals.sagepub.com
Even though routine screening of the general hospital population is discouraged, medical
laboratories may use a “lupus sensitive” activated partial thromboplastin time test (aPTT) …
laboratories may use a “lupus sensitive” activated partial thromboplastin time test (aPTT) …
Practical considerations and testing nuances for the detection of lupus anticoagulant: Do low phospholipid screen results, assay type, and test ratio matter?
Objectives Lupus anticoagulant (LA) detection requires (1) prolongation of a phospholipid
(PL)–dependent clot-based screening assay,(2) noncorrection upon adding normal pooled …
(PL)–dependent clot-based screening assay,(2) noncorrection upon adding normal pooled …
Diagnostic test combinations associated with thrombosis in lupus anticoagulant positive patients
K Devreese, K Peerlinck… - Thrombosis and …, 2011 - thieme-connect.com
The laboratory diagnosis of the antiphospholipid syndrome (APS) via antiphospholipid
antibody (aPL) tests, including lupus anticoagulant (LAC), anticardiolipin (aCL), or anti …
antibody (aPL) tests, including lupus anticoagulant (LAC), anticardiolipin (aCL), or anti …
Further evidence of false negative screening for lupus anticoagulants
GW Moore, A Henley, CK Greenwood… - Thrombosis research, 2008 - Elsevier
INTRODUCTION: Accurate and timely detection of lupus anticoagulants (LA) is of diagnostic
and prognostic importance due to the association of persistent LA with thrombotic disease …
and prognostic importance due to the association of persistent LA with thrombotic disease …
When to screen for lupus anticoagulant? Influence of testing during acute phase and consequences for clinical practise
J Ruinemans-Koerts, YM Ahmed-Ousenkova… - Lupus, 2015 - journals.sagepub.com
Sir, Diagnosis of the antiphospholipid syndrome (APS) is based on clinical criteria in
combination with the presence of antiphospholipid (aPL) antibodies. 1 Laboratory tests …
combination with the presence of antiphospholipid (aPL) antibodies. 1 Laboratory tests …
Real-world evidence of lupus anticoagulant testing: simultaneous positivity of diluted Russell's viper venom time and silica clotting time increases thrombotic risk …
Y Lee, JY Gu, HK Kim - Journal of Thrombosis and Thrombolysis, 2022 - Springer
Lupus anticoagulant (LA) is composed of heterogeneous autoantibodies, which have a
close association with thrombotic events. Due to its heterogeneity, two methods for …
close association with thrombotic events. Due to its heterogeneity, two methods for …
An evaluation of two commercial test procedures for the detection of lupus anticoagulant
R Schjetlein, F Wisl∅ ff - American journal of clinical pathology, 1995 - academic.oup.com
The authors have evaluated two commercial assays for lupus anticoagulants (LA), the
DVVtest+ DVVconfirm (American Diagnostica, Greenwich, CT) and the PTT-LA+ Staclot LA …
DVVtest+ DVVconfirm (American Diagnostica, Greenwich, CT) and the PTT-LA+ Staclot LA …
[HTML][HTML] Survey of lupus anticoagulant diagnosis by central evaluation of positive plasma samples
Objective: To determine whether the diagnosis of lupus anticoagulant (LAC) in a large
cohort of positive patients was confirmed at a reference laboratory. Methods: Over a 1‐year …
cohort of positive patients was confirmed at a reference laboratory. Methods: Over a 1‐year …
Lupus anticoagulant testing: dilute prothrombin time (dPT)
GW Moore - Hemostasis and Thrombosis: Methods and Protocols, 2023 - Springer
Lupus anticoagulants (LA) rarely affect routine prothrombin time assays because the high
phospholipid (PL) content in thromboplastin reagents tends to overwhelm the antibodies …
phospholipid (PL) content in thromboplastin reagents tends to overwhelm the antibodies …