Indoor radon in EGFR-and BRAF-mutated and ALK-rearranged non–small-cell lung cancer patients

L Mezquita, A Benito, A Ruano-Ravina, J Zamora… - Clinical Lung Cancer, 2019 - Elsevier
Background Radon gas is the leading cause of lung cancer in the nonsmoking population.
The World Health Organization (WHO) recommends indoor concentrations of< 100 Bq/m³ …

Residential radon, EGFR mutations and ALK alterations in never-smoking lung cancer cases

A Ruano-Ravina, M Torres-Durán… - European …, 2016 - Eur Respiratory Soc
The aim of this study was to assess if residential radon exposure might cause EGFR
mutations or ALK rearrangements in never-smokers. We designed a multicentre case …

1508TiP The 1920-EORTC-BIORADON study: Molecular characterization of non-small cell lung cancer (NSCLC) and indoor radon exposure in Europe

L Mezquita, F Turrisi, ME Mauer, C Mallien… - Annals of …, 2023 - annalsofoncology.org
Background Lung cancer is the leading cause of cancer death worldwide. Radon is a
radioactive gas tending to accumulate inside homes and it is considered one of the leading …

OA09. 06 molecular alterations and estimated indoor radon in NSCLC patients from the French National Cancer Institute registry: Radon France study

L Mezquita, F Barlesi, E Auclin, D Planchard… - Journal of Thoracic …, 2018 - jto.org
Background Radon is a radioactive gas, considered the leading cause of lung cancer in non-
smokers. We assessed the correlation between the radon exposure areas in France and the …

Radon and lung cancer: current trends and future perspectives

M Riudavets, M Garcia de Herreros, B Besse… - Cancers, 2022 - mdpi.com
Simple Summary Radon represents the main risk factor of lung cancer in non-smokers and
the second one in smoking patients. In Europe, there are several radon-prone areas, but …

Indoor radon exposure increases tumor mutation burden in never-smoker patients with lung adenocarcinoma

SM Lim, JW Choi, MH Hong, D Jung, CY Lee, SY Park… - Lung Cancer, 2019 - Elsevier
Objectives Radon, a natural radiation, is the leading environmental cause of lung cancer in
never-smokers. However, the radon exposure impact on the mutational landscape and …

OA13. 04 prevalence of molecular alterations in NSCLC and Estimated Indoor radon in Europe: RADON EUROPE Study

M Garcia, MG de Herreros, E Auclin, G Caravaca… - Journal of Thoracic …, 2022 - jto.org
Methods Retrospective analysis of NSCLC molecular data and radon data reported from all
European countries was performed. Demographic data were collected from the Worlds …

FP09. 05 Driver oncogenic alterations and indoor radon in NSCLC patients from the IFCT biomarker cohort: Bioradon France study

L Mezquita, F Barlesi, G Ielsch, J Merlio… - Journal of Thoracic …, 2021 - jto.org
Methods Retrospective assessment of patients with NSCLC tested for EGFR/BRAF/HER2/
KRAS mutations (m) and ALK fusion from the 28 Platform led by the National Cancer …

Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure

JR Choi, SY Park, OK Noh, YW Koh… - Annals of occupational and …, 2016 - Springer
Although the incidence and mortality for most cancers such as lung and colon are
decreasing in several countries, they are increasing in several developed countries because …

Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

G Gamerith, M Kloppenburg, F Mildner, A Amann… - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer (LC) is the leading cause of cancer death worldwide. After
smoking, one of the most prominent risk factors for LC development is radon (Rn) exposure …