Development of Magnet‐Driven and Image‐Guided Degradable Microrobots for the Precise Delivery of Engineered Stem Cells for Cancer Therapy

T Wei, J Liu, D Li, S Chen, Y Zhang, J Li, L Fan, Z Guan… - Small, 2020 - Wiley Online Library
Precise delivery of therapeutic cells to the desired site in vivo is an emerging and promising
cellular therapy in precision medicine. This paper presents the development of a magnet …

Development of a magnetic microrobot for carrying and delivering targeted cells

J Li, X Li, T Luo, R Wang, C Liu, S Chen, D Li, J Yue… - Science robotics, 2018 - science.org
The precise delivery of targeted cells through magnetic field–driven microrobots/carriers is a
promising technique for targeted therapy and tissue regeneration. This paper presents a …

Magnetically actuated microrobots as a platform for stem cell transplantation

S Jeon, S Kim, S Ha, S Lee, E Kim, SY Kim, SH Park… - Science Robotics, 2019 - science.org
Magnetic microrobots were developed for three-dimensional culture and the precise delivery
of stem cells in vitro, ex vivo, and in vivo. Hippocampal neural stem cells attached to the …

Precise control of customized macrophage cell robot for targeted therapy of solid tumors with minimal invasion

Y Dai, X Bai, L Jia, H Sun, Y Feng, L Wang, C Zhang… - Small, 2021 - Wiley Online Library
Injecting micro/nanorobots into the body to kill tumors is one of the ultimate ambitions for
medical nanotechnology. However, injecting current micro/nanorobots based on 3D‐printed …

Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct

L Su, D Jin, Y Wang, Q Wang, C Pan, S Jiang… - Science …, 2023 - science.org
The magnetic microrobots promise benefits in minimally invasive cell-based therapy.
However, they generally suffer from an inevitable compromise between their magnetic …

Multifunctional microrobot with real-time visualization and magnetic resonance imaging for chemoembolization therapy of liver cancer

G Go, A Yoo, KT Nguyen, M Nan, BA Darmawan… - Science …, 2022 - science.org
Microrobots that can be precisely guided to target lesions have been studied for in vivo
medical applications. However, existing microrobots have challenges in vivo such as …

Recent progress in magnetically actuated microrobots for targeted delivery of therapeutic agents

J Choi, J Hwang, J Kim, H Choi - Advanced Healthcare …, 2021 - Wiley Online Library
Therapeutic agents, such as drugs and cells, play an essential role in virtually every
treatment of injury, illness, or disease. However, the conventional practices of drug delivery …

A magnetically guided self‐rolled microrobot for targeted drug delivery, real‐time X‐Ray imaging, and microrobot retrieval

KT Nguyen, G Go, Z Jin, BA Darmawan… - Advanced …, 2021 - Wiley Online Library
Targeted drug delivery using a microrobot is a promising technique capable of overcoming
the limitations of conventional chemotherapy that relies on body circulation. However, most …

Hybrid-actuating macrophage-based microrobots for active cancer therapy

J Han, J Zhen, V Du Nguyen, G Go, Y Choi, SY Ko… - Scientific reports, 2016 - nature.com
Using macrophage recruitment in tumors, we develop active, transportable, cancer
theragnostic macrophage-based microrobots as vector to deliver therapeutic agents to tumor …

A biodegradable magnetic microrobot based on gelatin methacrylate for precise delivery of stem cells with mass production capability

S Noh, S Jeon, E Kim, U Oh, D Park, SH Park, SW Kim… - Small, 2022 - Wiley Online Library
A great deal of research has focused on small‐scale robots for biomedical applications and
minimally invasive delivery of therapeutics (eg, cells, drugs, and genes) to a target area …