Maternal Exposure to PM2.5 during Pregnancy Induces Impaired Development of Cerebral Cortex in Mice Offspring

T Zhang, X Zheng, X Wang, H Zhao, T Wang… - International journal of …, 2018 - mdpi.com
Air pollution is a serious environmental health problem closely related to the occurrence of
central nervous system diseases. Exposure to particulate matter with an aerodynamic …

Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus

MW Chao, CH Yang, PT Lin, YH Yang… - Environmental …, 2017 - Wiley Online Library
ABSTRACT PM2. 5 travels along the respiratory tract and enters systemic blood circulation.
Studies have shown that PM2. 5 increases the incidence of various diseases not only in …

Gestational Exposure to Particulate Matter 2.5 (PM2.5) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring

X Zheng, X Wang, T Wang, H Zhang, H Wu… - Frontiers in …, 2019 - frontiersin.org
Prenatal exposure to air pollutants has long-term impact on growth retardation of nervous
system development and is related to central nervous system diseases in children. However …

[HTML][HTML] Gestational exposure to PM2. 5 leads to cognitive dysfunction in mice offspring via promoting HMGB1-NLRP3 axis mediated hippocampal inflammation

T Zhang, L Sun, T Wang, C Liu, H Zhang… - Ecotoxicology and …, 2021 - Elsevier
PM 2.5 is recently identified as a kind of material possessing severe biohazard. It can enter
human body and exerts pathological effects on lung, eyes, and the central nervous system …

Metabolomics analysis explores the rescue to neurobehavioral disorder induced by maternal PM2. 5 exposure in mice

J Cui, Y Fu, R Lu, Y Bi, L Zhang, C Zhang… - Ecotoxicology and …, 2019 - Elsevier
Reproductive epidemiological studies have suggested associations between perinatal
exposure to fine particulate matter (PM 2.5) and adverse birth outcomes. To explore the …

Neurodevelopmental toxicity induced by maternal PM2. 5 exposure and protective effects of quercetin and Vitamin C

M Zhang, W Liu, Y Zhou, Y Li, Y Qin, Y Xu - Chemosphere, 2018 - Elsevier
Epidemiological studies show that maternal exposure to PM 2.5 affects the
neurodevelopment of the offspring, especially the neurocognitive function. However, no …

[HTML][HTML] Gestational B-vitamin supplementation alleviates PM2. 5-induced autism-like behavior and hippocampal neurodevelopmental impairment in mice offspring

T Wang, T Zhang, L Sun, W Li, C Zhang, L Yu… - Ecotoxicology and …, 2019 - Elsevier
Gestational exposure to PM 2.5 is a worldwide environmental issue associated with long-
lasting behavior abnormalities and neurodevelopmental impairments in the hippocampus of …

Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy

C Zhao, P Xie, T Yong, W Huang, J Liu, D Wu, F Ji, M Li… - Science Bulletin, 2021 - Elsevier
Gestational exposure to PM 2.5 is associated with adverse postnatal outcomes. PM 2.5 can
enter alveoli by using intratracheal instillation, even penetrate through lung cells into the …

Gestational exposure to PM2. 5 impairs vascularization of the placenta

H Yue, X Ji, Y Zhang, G Li, N Sang - Science of The Total Environment, 2019 - Elsevier
The placenta is the bridge that connects the developing fetus and mother and is the place
where nutrient uptake, waste elimination and gas exchange occurs. Epidemiological studies …

Transgenerational transmission of neurodevelopmental disorders induced by maternal exposure to PM2. 5

Y Zhou, M Zhang, W Liu, Y Li, Y Qin, Y Xu - Chemosphere, 2020 - Elsevier
The pathological traits or diseases susceptibility caused by maternal exposure to
environmental adverse insults (infection, malnutrition, environmental toxicants) could be …