An aspalathin-rich green rooibos extract (Afriplex GRT™) has demonstrated anti-diabetic
and hypolipidemic properties, while also moderately inhibiting CYP3A4 activity, suggesting …

Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to
prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis) …

Objectives To explore the effect of Acai berry on the pharmacokinetics of Atorvastatin (ATR),
Alogliptin (ALO) and Empagliflozin (EMPA) in SD rats. Method Thirty-six rats were divided …

Background: Green tea can inhibit OATPs, so it may interact with the substrate of OATPs,
such as rosuvastatin. Objective: This study aimed to investigate the effects of green tea on …

This study aimed to investigate the potential impact of epigallocatechin-3-gallate (EGCG) on
the pharmacokinetic behaviors of simvastatin and its metabolite simvastatin acid and …

Ethnopharmacological relevance Ginkgo biloba L. is a traditional Chinese medicine for
hyper lipaemia. Ginkgo flavonols and terpene lactones are responsible for the lipid-lowering …

Berberine, a quinoline alkaloid, can be used in combination with statins to enhance
hypolipidemic effects and reduce the dose and side effects of statins. The hypolipidemic …

Ginkgo biloba extract (GBE) is one of the most widely used herbal medicines in the world. It
is often administered in combination with statins to treat diseases, especially some nervous …

Theaflavins (TFs) are derived from black tea, an important source of dietary polyphenols.
Although the potential interactions between dietary polyphenols and drugs have been …

Objective: To assess pharmacokinetic interaction of garlic with atorvastatin in dyslipidemic
rats. Materials and Methods: Sprague Dawley rats with induced dyslipidemia were divided …