Genetics of neural tube defects

JG Hall, F Solehdin - Mental retardation and developmental …, 1998 - Wiley Online Library
Neural tube defects are a complex, heterogeneous, and multifactorial group of disorders. In
humans it is estimated that 80% of neural tube defects are “multifactorial” and are influenced …

Human neural tube defects: genetic causes and prevention

P De Marco, E Merello, A Cama, Z Kibar, V Capra - Biofactors, 2011 - Wiley Online Library
Neural tube defects (NTDs) are severe congenital malformations affecting 1–2 in 1,000 live
births, whose etiology is multifactorial, involving environmental and genetic factors. NTDs …

Epidemiology of neural tube defects

LE Mitchell - American Journal of Medical Genetics Part C …, 2005 - Wiley Online Library
The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …

Genetic basis of neural tube defects

AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

Current perspectives on the genetic causes of neural tube defects

P De Marco, E Merello, S Mascelli, V Capra - neurogenetics, 2006 - Springer
Neural tube defects (NTDs) are a group of severe congenital abnormalities resulting from
the failure of neurulation. The pattern of inheritance of these complex defects is …

Etiology, pathogenesis and prevention of neural tube defects

R Padmanabhan - Congenital anomalies, 2006 - Wiley Online Library
Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

Neural tube defects in the sample of genetic counselling

JG Joó, A Beke, C Papp, E Tóth‐Pál… - … in Affiliation With the …, 2007 - Wiley Online Library
Objective This study was conducted to evaluate the major demographic details, diagnostical
and clinical features, as well as the risk of recurrence of cases with the major types of neural …

Epidemiology of neural tube defects and folic acid

DB Shurtleff - Cerebrospinal fluid research, 2004 - Springer
This review article combines four disparate observations about Neural Tube Defects (NTDs).
They are the worldwide decline in the birth incidence that began prior to prenatal diagnosis; …

[HTML][HTML] Folic acid and neural tube defects

HV Toriello - Genetics in Medicine, 2005 - nature.com
Major congenital anomalies occur in 2% to 3% of live births. Neural tube defects (NTDs),
cleft lip and palate, and cardiac anomalies are some of the most common. NTDs are a group …

Investigations into the etiology of neural tube defects

RM Cabrera, DS Hill, AJ Etheredge… - Birth Defects Research …, 2004 - Wiley Online Library
Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …