Multi‐site neural tube closure in humans and maternal folate supplementation

MJ Seller - American journal of medical genetics, 1995 - Wiley Online Library
A group of 13 individuals with neural tube defects (NTD) despite maternal periconceptional
folate supplementation was examined to determine precisely which closure sites along the …

The etiology of neural tube defects: the role of folic acid

DG McLone - Child's Nervous System, 2003 - Springer
Discussion While the cause of neural tube defects in humans is considered to be
multifactorial, it is apparent that folic acid can prevent 70% of open neural tube defects. Even …

Folate and neural tube defects

C Bower - Nutrition reviews, 1995 - search.proquest.com
Folate and Neural Tube Defects Page 1 September 1995: ”0333—838 Folate and Neural
Tube Defects Carol Bower, Ph.D., FAFPHM Neural tube defects (anencephaly; spina bifida …

Neural tube defects

NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Pathophysiology, prevention, and potential treatment of neural tube defects

SM Manning, R Jennings… - Mental retardation and …, 2000 - Wiley Online Library
Neural tube defects (NTD) remain a major cause of morbidity in spite of the reduction in
liveborn incidence with periconceptional folic acid. However, the etiology remains unknown …

[HTML][HTML] Policy statement on folic acid and neural tube defects

HV Toriello - Genetics IN Medicine, 2011 - Elsevier
It now recognized that the use of folate fortification and/or supplementation before initiation
of pregnancy can impact the risk of the fetus developing a neural tube defect. This document …

Studies in neural tube defects I. Epidemiologic and etiologic aspects

NC Myrianthopoulos, M Melnick… - American journal of …, 1987 - Wiley Online Library
Abstract In the NIH Collaborative Perinatal Project, a prospective study of over 53,000
pregnant women and their offspring, 71 single‐born children (13.33/10,000) were found to …

Genetics of neural tube defects

J Gelineau-van Waes, RH Finnell - Seminars in Pediatric Neurology, 2001 - Elsevier
Neural tube defects (NTDs) are common congenital malformations that occur when the
embryonic neural tube fails to close properly during early development. Although …

Genetic heterogeneity in neural tube defects.

JL Simpson, J Mills, GG Rhoads… - Annales de …, 1991 - europepmc.org
In 1985-1987, the authors attempted to ascertain all cases of confirmed neural tube defects
(NTD) in California and Illinois, not only among live-born infants (postnatal) but also cases …

Toward understanding the genetic basis of neural tube defects

Z Kibar, V Capra, P Gros - Clinical genetics, 2007 - Wiley Online Library
Neural tube defects (NTDs) represent a common group of severe congenital malformations
that result from failure of neural tube closure during early development. Their etiology is …