Folic acid has been demonstrated in clinical trials to reduce significantly the recurrence (and
probably occurrence) of neural tube defects (NTD). In the UK, there has been no decline in …

Neural tube defects may due to a number of factors acting on a susceptible embryo. The
most widely accepted is a lack of folic acid at a critical time of development. Studies in which …

Vitamin levels were measured in twenty women under 35 years of age with a history of two
or more neural tube defect pregnancies. Each index case was compared with a female …

• Objective.—To describe the recent trends and epidemiologic characteristics of neural tube
defects in the United States. Research Design.—Ongoing surveillance data. Setting.—Two …

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Introduction Multiple genetic and epigenetic factors involved in central nervous system
(CNS) development influence the incidence of neural tube defects (NTDs). Discussion The …

Neural tube defects (NTDs) are among the commonest human birth defects, affecting around
1 per 1,000 births [Copp et al., 2003]. A genetic basis for NTDs is implicated based on the …

OBJECTIVE:: Severe neural tube defects (NTDs) tend to occur with disproportionate
frequency in areas of high prevalence. The objective of our study was to determine the birth …

The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …

Neural tube defects (NTDs) constitute a major health burden (0.5-2/1000 pregnancies
worldwide), and remain a preventable cause of still birth, neonatal, and infant death, or …