[HTML][HTML] Interpretable tumor differentiation grade and microsatellite instability recognition in gastric cancer using deep learning

F Su, J Li, X Zhao, B Wang, Y Hu, Y Sun, J Ji - Laboratory Investigation, 2022 - Elsevier
Gastric cancer possesses great histological and molecular diversity, which creates obstacles
for rapid and efficient diagnoses. Classic diagnoses either depend on the pathologist's …

Clinical actionability of triaging DNA mismatch repair deficient colorectal cancer from biopsy samples using deep learning

W Jiang, WJ Mei, SY Xu, YH Ling, WR Li, JB Kuang… - …, 2022 - thelancet.com
Background We aimed to develop a deep learning (DL) model to predict DNA mismatch
repair (MMR) status in colorectal cancers (CRC) based on hematoxylin and eosin-stained …

Predicting tumour mutational burden from histopathological images using multiscale deep learning

MS Jain, TF Massoud - Nature Machine Intelligence, 2020 - nature.com
Tumour mutational burden (TMB) is an important biomarker for predicting the response to
immunotherapy in patients with cancer. Gold-standard measurement of TMB is performed …

[HTML][HTML] Role of artificial intelligence in digital pathology for gynecological cancers

YL Wang, S Gao, Q Xiao, C Li, M Grzegorzek… - Computational and …, 2024 - Elsevier
The diagnosis of cancer is typically based on histopathological sections or biopsies on glass
slides. Artificial intelligence (AI) approaches have greatly enhanced our ability to extract …

[HTML][HTML] Predicting oncogene mutations of lung cancer using deep learning and histopathologic features on whole-slide images

N Tomita, LJ Tafe, AA Suriawinata, GJ Tsongalis… - Translational …, 2022 - Elsevier
Lung cancer is a leading cause of death in both men and women globally. The recent
development of tumor molecular profiling has opened opportunities for targeted therapies for …

Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning

J Höhn, E Krieghoff-Henning, C Wies, L Kiehl… - NPJ Precision …, 2023 - nature.com
Studies have shown that colorectal cancer prognosis can be predicted by deep learning-
based analysis of histological tissue sections of the primary tumor. So far, this has been …

[HTML][HTML] Deep learning-based diagnosis of lung cancer using a nationwide respiratory cytology image set: improving accuracy and inter-observer variability

T Kim, H Chang, B Kim, J Yang, D Koo… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Deep learning (DL)-based image analysis has recently seen widespread application in
digital pathology. Recent studies utilizing DL in cytopathology have shown promising …

End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study

X Jiang, M Hoffmeister, H Brenner, HS Muti… - The Lancet Digital …, 2024 - thelancet.com
Background Precise prognosis prediction in patients with colorectal cancer (ie, forecasting
survival) is pivotal for individualised treatment and care. Histopathological tissue slides of …

Quantitative digital histopathology and machine learning to predict pathological complete response to chemotherapy in breast cancer patients using pre-treatment …

K Saednia, A Lagree, MA Alera, L Fleshner, A Shiner… - Scientific Reports, 2022 - nature.com
Complete pathological response (pCR) to neoadjuvant chemotherapy (NAC) is a prognostic
factor for breast cancer (BC) patients and is correlated with improved survival. However …

Direct prediction of genetic aberrations from pathology images in gastric cancer with swarm learning

OL Saldanha, HS Muti, HI Grabsch, R Langer, B Dislich… - Gastric cancer, 2023 - Springer
Background Computational pathology uses deep learning (DL) to extract biomarkers from
routine pathology slides. Large multicentric datasets improve performance, but such …