Myocardial interstitial fibrosis in heart failure: biological and translational perspectives
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …
development of heart failure. Basic research has provided abundant evidence for the …
Myocardial Interstitial Fibrosis in Nonischemic Heart Disease, Part 3/4: JACC Focus Seminar
J Díez, A González, JC Kovacic - Journal of the American College of …, 2020 - jacc.org
Myocardial interstitial fibrosis (MIF) is a histological hallmark of several cardiac diseases that
alter myocardial architecture and function and are associated with progression to heart …
alter myocardial architecture and function and are associated with progression to heart …
Myocardial fibrosis: biomedical research from bench to bedside
M Gyöngyösi, J Winkler, I Ramos, QT Do… - European journal of …, 2017 - Wiley Online Library
Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial
myocardial collagen network that occur in response to cardiac ischaemic insults, systemic …
myocardial collagen network that occur in response to cardiac ischaemic insults, systemic …
Diffuse myocardial fibrosis: mechanisms, diagnosis and therapeutic approaches
B López, S Ravassa, MU Moreno, GS José… - Nature Reviews …, 2021 - nature.com
Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …
[HTML][HTML] Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies
S Ravassa, B López, TA Treibel, G San José… - Molecular Aspects of …, 2023 - Elsevier
Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …
resulting from the excessive deposition of collagen fibers, is a common feature across the …
[HTML][HTML] Current understanding of the pathophysiology of myocardial fibrosis and its quantitative assessment in heart failure
T Liu, D Song, J Dong, P Zhu, J Liu, W Liu, X Ma… - Frontiers in …, 2017 - frontiersin.org
Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and
death. Myocardial fibrosis results from increased myofibroblast activity and excessive …
death. Myocardial fibrosis results from increased myofibroblast activity and excessive …
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure …
RA de Boer, G De Keulenaer… - European journal of …, 2019 - Wiley Online Library
Fibrosis is a pivotal player in heart failure development and progression. Measurements of
(markers of) fibrosis in tissue and blood may help to diagnose and risk stratify patients with …
(markers of) fibrosis in tissue and blood may help to diagnose and risk stratify patients with …
[HTML][HTML] Current understanding of fibrosis in genetic cardiomyopathies
Myocardial fibrosis is the excessive deposition of extracellular matrix proteins, including
collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or …
collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or …
Imaging interstitial fibrosis, left ventricular remodeling, and function in stage A and B heart failure
T Pezel, M Viallon, P Croisille, L Sebbag… - Cardiovascular …, 2021 - jacc.org
Myocardial interstitial fibrosis is part of the advanced disease stage of most cardiovascular
pathologies. It has been characterized histologically in various disease settings from …
pathologies. It has been characterized histologically in various disease settings from …
Prognostic Impact of Myocardial Interstitial Fibrosis in Non-Ischemic Heart Failure–Comparison Between Preserved and Reduced Ejection Fraction Heart Failure–
T Aoki, Y Fukumoto, K Sugimura, M Oikawa… - Circulation …, 2011 - jstage.jst.go.jp
Background: Although myocardial fibrosis plays an important role in the progression of heart
failure (HF), its prognostic impact still remains to be clarified. Methods and Results: A total of …
failure (HF), its prognostic impact still remains to be clarified. Methods and Results: A total of …
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