Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Myocardial interstitial fibrosis (MIF) is a histological hallmark of several cardiac diseases that
alter myocardial architecture and function and are associated with progression to heart …

Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial
myocardial collagen network that occur in response to cardiac ischaemic insults, systemic …

Diffuse myocardial fibrosis resulting from the excessive deposition of collagen fibres through
the entire myocardium is encountered in a number of chronic cardiac diseases. This lesion …

Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …

Myocardial fibrosis is an important part of cardiac remodeling that leads to heart failure and
death. Myocardial fibrosis results from increased myofibroblast activity and excessive …

Fibrosis is a pivotal player in heart failure development and progression. Measurements of
(markers of) fibrosis in tissue and blood may help to diagnose and risk stratify patients with …

Myocardial fibrosis is the excessive deposition of extracellular matrix proteins, including
collagens, in the heart. In cardiomyopathies, the formation of interstitial fibrosis and/or …

Myocardial interstitial fibrosis is part of the advanced disease stage of most cardiovascular
pathologies. It has been characterized histologically in various disease settings from …

Background: Although myocardial fibrosis plays an important role in the progression of heart
failure (HF), its prognostic impact still remains to be clarified. Methods and Results: A total of …