Transcriptional regulation of dendritic cell development and function
Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …
and adaptive immune systems. Extensive research addressing the cellular origin and …
[HTML][HTML] Transcriptional regulation of DC fate specification
C Bosteels, CL Scott - Molecular immunology, 2020 - Elsevier
Dendritic cells function in the immune system to instruct adaptive immune cells to respond
accordingly to different threats. While conventional dendritic cells can be subdivided into two …
accordingly to different threats. While conventional dendritic cells can be subdivided into two …
Transcriptional control of dendritic cell development and functions
L Amon, CHK Lehmann, A Baranska, J Schoen… - International review of …, 2019 - Elsevier
Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT
The functional diversification of dendritic cells (DCs) is a key step in establishing protective
immune responses. Despite the importance of DC lineage diversity, its genetic basis is not …
immune responses. Despite the importance of DC lineage diversity, its genetic basis is not …
Transcriptional networks driving dendritic cell differentiation and function
Dendritic cells (DCs) are the sentinels of the immune system, sensing a diverse array of
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
Models of dendritic cell development correlate ontogeny with function
DA Anderson III, KM Murphy - Advances in immunology, 2019 - Elsevier
Rapid advances have been made to uncover the mechanisms that regulate dendritic cell
(DC) development, and in turn, how models of development can be employed to define …
(DC) development, and in turn, how models of development can be employed to define …
[HTML][HTML] Development and function of dendritic cell subsets
A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
Transcriptional basis of mouse and human dendritic cell heterogeneity
CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …
their unique ability to initiate T cell responses and direct their differentiation into effector …
Classical DC2 subsets and monocyte‐derived DC: Delineating the developmental and functional relationship
RA Backer, HC Probst… - European journal of …, 2023 - Wiley Online Library
To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are
highly heterogeneous and comprise many specialized subtypes, including conventional DC …
highly heterogeneous and comprise many specialized subtypes, including conventional DC …
[HTML][HTML] The ontogenetic path of human dendritic cells
L Amon, CHK Lehmann, L Heger, GF Heidkamp… - Molecular …, 2020 - Elsevier
Dendritic cells (DCs) orchestrate adaptive immune responses. In healthy individuals, DCs
are drivers and fine-tuners of T cell responses directed against invading pathogens or …
are drivers and fine-tuners of T cell responses directed against invading pathogens or …