Transcriptional regulation of dendritic cell development and function

S Zhang, C Audiger, M Chopin, SL Nutt - Frontiers in immunology, 2023 - frontiersin.org
Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …

[HTML][HTML] Transcriptional regulation of DC fate specification

C Bosteels, CL Scott - Molecular immunology, 2020 - Elsevier
Dendritic cells function in the immune system to instruct adaptive immune cells to respond
accordingly to different threats. While conventional dendritic cells can be subdivided into two …

Transcriptional control of dendritic cell development and functions

L Amon, CHK Lehmann, A Baranska, J Schoen… - International review of …, 2019 - Elsevier
Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …

Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT

S Zhang, HD Coughlan, M Ashayeripanah… - Science …, 2021 - science.org
The functional diversification of dendritic cells (DCs) is a key step in establishing protective
immune responses. Despite the importance of DC lineage diversity, its genetic basis is not …

Transcriptional networks driving dendritic cell differentiation and function

SL Nutt, M Chopin - Immunity, 2020 - cell.com
Dendritic cells (DCs) are the sentinels of the immune system, sensing a diverse array of
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …

Models of dendritic cell development correlate ontogeny with function

DA Anderson III, KM Murphy - Advances in immunology, 2019 - Elsevier
Rapid advances have been made to uncover the mechanisms that regulate dendritic cell
(DC) development, and in turn, how models of development can be employed to define …

[HTML][HTML] Development and function of dendritic cell subsets

A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …

Transcriptional basis of mouse and human dendritic cell heterogeneity

CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

Classical DC2 subsets and monocyte‐derived DC: Delineating the developmental and functional relationship

RA Backer, HC Probst… - European journal of …, 2023 - Wiley Online Library
To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are
highly heterogeneous and comprise many specialized subtypes, including conventional DC …

[HTML][HTML] The ontogenetic path of human dendritic cells

L Amon, CHK Lehmann, L Heger, GF Heidkamp… - Molecular …, 2020 - Elsevier
Dendritic cells (DCs) orchestrate adaptive immune responses. In healthy individuals, DCs
are drivers and fine-tuners of T cell responses directed against invading pathogens or …