ABSTRACT A key problem in evolutionary developmental biology is identifying the sources
of instructive information that determine species-specific anatomical pattern. Understanding …

Understanding how organisms establish their form during embryogenesis and regeneration
represents a major knowledge gap in biological pattern formation. It has been recently …

Gene regulatory networks (GRNs) describe interactions between gene products and
transcription factors that control gene expression. In combination with reaction–diffusion …

A critical aspect of evolution is the layer of developmental physiology that operates between
the genotype and the anatomical phenotype. While much work has addressed the evolution …

One lens with which to understand the complex phenomenon of cancer is that of
developmental biology. Cancer is the inevitable consequence of a breakdown of the …

The field of tissue engineering is moving toward a new concept of “in vitro biomimetics of in
vivo tissue development.” In Part I of this series, we proposed a theoretical framework …

Highlights•Synthetic developmental biology is an emerging area of science that integrates
synthetic biology and developmental biology.•Developmental mechanisms can be …

Recent advances in molecular biology such as gene editing [1], bioelectric recording and
manipulation [2] and live cell microscopy using fluorescent reporters [3],[4]–especially with …

It is well known that electrical signals are deeply associated with living entities. Much of our
understanding of excitable tissues is derived from studies of specialized cells of neurons or …

How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …