Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia,
characterized by an accumulation of abnormal promyelocytes in the bone marrow, a severe …

Acute promyelocytic leukemia (APL), comprises 5-7% of acute myeloid leukemias (AML),
and is typically characterized by the reciprocal translocation t (15; 17)(q22; q21), resulting in …

Acute promyelocytic leukemia (APL) is typified by t (15; 17)(q22; q21), generating the
promyelocytic leukemia (PML) gene at 15q22 with the retinoic acid α‑receptor (RARA) gene …

Acute promyelocytic leukemia (APL) is a distinct hematologic disorder characterized by
specific clinical, cytological, cytogenetic, and molecular features. It is associated with a …

Acute promyelocytic leukaemia (APL) is characterized by t (15; 17)(q22; q21) which results
in the formation of two chimaeric genes, PML/RARα and RARα/PML, thought to play a role in …

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation, t (15;
17)(q22; q12), resulting in fusion of the genes promyelocytic leukemia (PML) and retinoic …

Acute promyelocytic leukemia is a myeloid disorder that is characterized by the specific t (15;
17) variant in~ 98% of cases. The typical hypergranular and microgranular or hypogranular …

It is important to detect PML/RARa rearrangement in patient with morphologic acute
promyelocytic leukemia (APL). Rare cases of APL lacking the classic t (15; 17) on routine …

Acute promyelocytic leukemia (APL) is distinguished from other types of acute myeloid
leukemia by particular morphologic features. Management and prognosis of APL is …

Acute promyelocytic leukemia (APL; M3) is specifically characterized by a predominance of
malignant promyelocytes having atypical reciprocal translocation involving chromosome 15 …