Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects

F Hassan, MS Rehman, MS Khan, MA Ali… - Frontiers in …, 2019 - frontiersin.org
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …

“Curcumin, the king of spices”: epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases

SSS Boyanapalli, ANT Kong - Current pharmacology reports, 2015 - Springer
Curcumin (diferuloylmethane), a polyphenolic compound, is a component of Curcuma
longa, commonly known as turmeric. It is a well-known anti-inflammatory, anti-oxidative, and …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Epigenetic changes induced by curcumin and other natural compounds

S Reuter, SC Gupta, B Park, A Goel, BB Aggarwal - Genes & nutrition, 2011 - Springer
Epigenetic regulation, which includes changes in DNA methylation, histone modifications,
and alteration in microRNA (miRNA) expression without any change in the DNA sequence …

Curcumin as a regulator of epigenetic events

MH Teiten, M Dicato, M Diederich - Molecular nutrition & food …, 2013 - Wiley Online Library
Epigenetic alterations correspond to changes in DNA methylation, covalent modifications of
histones, or altered mi RNA expression patterns. These three mechanisms are …

Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition

K Fabianowska-Majewska, A Kaufman-Szymczyk… - Nutrients, 2021 - mdpi.com
One of the most systematically studied bioactive nutraceuticals for its benefits in the
management of various diseases is the turmeric-derived compounds: curcumin. Turmeric …

Development of curcumin as an epigenetic agent

S Fu, R Kurzrock - Cancer, 2010 - Wiley Online Library
The clinical benefits of curcumin as a single agent were demonstrated in patients with
advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a …

Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways

AH Rahmani, MA Al Zohairy, SM Aly… - BioMed research …, 2014 - Wiley Online Library
Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact
cause of cancer development and progression is not fully known. But it is thought that cancer …

The functional genomic studies of curcumin

L Huminiecki, J Horbańczuk, AG Atanasov - Seminars in cancer biology, 2017 - Elsevier
Curcumin is a natural plant-derived compound that has attracted a lot of attention for its anti-
cancer activities. Curcumin can slow proliferation of and induce apoptosis in cancer cell …

Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives

G Kumar, S Mittal, K Sak, HS Tuli - Life sciences, 2016 - Elsevier
In recent years, natural compounds have received considerable attention in preventing and
curing most dreadful diseases including cancer. The reason behind the use of natural …